Sökning: "oligodendrocyte progenitor cell"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden oligodendrocyte progenitor cell.

  1. 1. Cellular Origin and Development of Glioma

    Författare :Nanna Lindberg; Lene Uhrbom; Bengt Westermark; Kristian Pietras; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioma; brain tumor; PDGF; RCAS TV-A; cell of origin; glial cell; oligodendrocyte progenitor cell; DNA repair; homology-directed repair; RAD51; angiogenesis; histidine-rich glycoprotein; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; Molecular Medicine; molekylär medicin genetik och patologi ;

    Sammanfattning : Gliomas are the most common primary tumors of the central nervous system believed to arise from glial cells. Invasive growth and inherent propensity for malignant progression make gliomas incurable despite extensive treatment. LÄS MER

  3. 2. Oligodendrocyte pathology following Traumatic Brain Injury : Experimental and clinical studies

    Författare :Johanna Flygt; Niklas Marklund; Fredrik Piehl; Uppsala universitet; []
    Nyckelord :Traumatic brain injury; oligodendrocytes; oligodendrocyte progenitor cells; interleukin 1-β; central fluid percussion injury; Neurokirurgi; Neurosurgery; Neurokirurgi; Neurosurgery;

    Sammanfattning : Traumatic brain injury (TBI) caused by traffic and fall accidents, sports-related injuries and violence commonly results in life-changing disabilities. Cognitive impairments following TBI may be due to disruption of axons, stretched by the acceleration/deceleration forces of the initial impact, and their surrounding myelin in neuronal networks. LÄS MER

  4. 3. Opioids regulate proliferation of neural progenitors. A study on the effects of opioids on adult rat hippocampal progenitors in vitro and in vivo

    Författare :Anders I. Persson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Opioid; brain; hippocampus; rat; neurogenesis; progenitor; stem cell; b-endorphin; calcium; MAPK;

    Sammanfattning : The opioid receptors were among the first pharmacologically described brain receptors. These opioid receptors have thereafter been shown to mediate effects on proliferation and differentiation in both the embryonal and adult central nervous system. LÄS MER

  5. 4. Cell states along oligodendrocyte development and disease

    Författare :David van Bruggen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The brain, one of the most complex organs in the body, where an immense diversity of cell states emerges from simple structure, where function arises from sets of regulatory principles and pattern persist where individual cells do not. Revealing the regulatory underpinnings of the brain, from unspecified cell states to diversity, is paramount for achieving a thorough understanding of the development process and generating insight into the disease states of the brain. LÄS MER

  7. 5. Neural stem cell therapy and inflammation status of post-traumatic syringomyelia

    Författare :Tingting Xu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Post-traumatic syringomyelia (PTS) is a severe complication of chronic spinal cord injury (SCI) with intraspinal expanding cysts as the major pathology. PTS occurs in up to 30 % of SCI patients, and time of diagnosis is usually years after the primary injury. LÄS MER