Sökning: "oil resistant"

Visar resultat 11 - 15 av 26 avhandlingar innehållade orden oil resistant.

  1. 11. Immunologic and genetic studies of rat adjuvant-induced arthritis

    Författare :Åsa Jansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :arthritis; autoimmunity; adjuvant; incomplete Freund s adjuvant; squalene; quantitative trait locus;

    Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory joint disease with a multifactorial and largely unknown etiology. It is influenced by both environmental and genetic factors, and understanding of disease mechanisms and identification of disease-causing genes is hampered by the complex and polygenic nature of the disease. LÄS MER

  2. 12. Pathogenesis of arthritis in rats : genetic factors and inducing molecules

    Författare :Johnny C Lorentzen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :arthritis; adjuvants; autoimmunity; MHC; genetics; rat; cytokines;

    Sammanfattning : Rheumatoid Arthritis (RA) is a chronic joint disease for which there is presently no cure, possibly because rational design of therapy is hindered by lack of knowledge of disease mechanisms (pathogenesis), and disease causing genetic and inducing factors (etiology). In this thesis, etiopathogenetic clues were sought in experimental arthritis, induced in different rat strains using both specific and nonspecific triggers of the immune system, i. LÄS MER

  3. 13. Short-Chain Fatty Acid Starch Stabilized Pickering Emulsions : Design, Properties and Applications

    Författare :Nabilah Binti Abdul Hadi; Avdelningen för livsmedel och läkemedel; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Short-chain fatty acid starch; Physicochemical properties; Pickering emulsions; Starch modification; Emulsion stability; Starch hydrolysis; In vitro digestion; Lipolysis;

    Sammanfattning : Pickering emulsions are emulsions stabilized by solid particles. Particles with optimal dual wettability toward both of the oil and water phases, can be adsorbed onto the interface, thereby providing the stability of the emulsions. LÄS MER

  4. 14. Translational Tumor Drug Delivery : Doxorubicin formulation performance, intracellular uptake and molecular diffusion

    Författare :Oliver Degerstedt; Hans Lennernäs; Erik Sjögren; Per Hansson; Jessica Rosenholm; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; doxorubicin; drug diffusion; cellular uptake; drug delivery; PBPK modelling; hepatocellular carcinoma; emulsion; IC50; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Globally, hepatocellular carcinoma (HCC) is the most common form of liver cancer and a leading cause of cancer death. One important risk factor is liver cirrhosis and the disease progression is characterized by deposition of extracellular matrix proteins that form a fibrous network, which increases liver stiffness and may limit the effectiveness of different treatment strategies. LÄS MER

  5. 15. Murine plasmacytomagenesis : an experimental model of B-cell neoplasia

    Författare :Santiago C Silva; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :mouse plasmacytomas; chromosomal translocation; chimeric mice; MYC-transgenic mice; ;

    Sammanfattning : A chromosomal translocation which results in the illegitimate activation of the c-myc proto-oncogene by one of the three immunoglobulin (Ig) loci is invariably associated with human Burkitt's Lymphoma (BL), mouse plasmacytoma (MPC) and rat immunocytomas (RIC). In the MPC system a genetic predisposition linked to the BALB/c strain has been suggested. LÄS MER