Sökning: "oestrogen receptor"
Visar resultat 11 - 15 av 36 avhandlingar innehållade orden oestrogen receptor.
11. Involvement of vasopressin and oxytocin in the regulation of human uterine activity
Sammanfattning : Vasopressin and oxytocin seem to have pivotal roles in the pathophysiology of primary dysmenorrhoea and preterm labour. Prostaglandins are also involved in the regulation of uterine activity with different receptors mediating both stimulation and relaxation. LÄS MER
12. Elucidating the role of 17β hydroxysteroid dehydrogenase type 14 in normal physiology and in breast cancer
Sammanfattning : Oestrogens play key roles in the development of the majority of breast tumours, a fact that has been exploited successfully in treating breast cancer with tamoxifen, which is a selective oestrogen receptor modulator. In post-menopausal women, oestrogens are synthesised in peripheral hormone-target tissues from adrenally derived precursors. LÄS MER
13. Endometrial carcinoma : steroid hormones and receptors in relation to proliferation
Sammanfattning : The significance of the hormonal milieu for endometrial changes is as well-known as its link with endometrial carcinoma. Unopposed oestradiol treatment is shown to increase the incidence for this cancer. Obesity leads to elevated levels of oestrogens and is a risk factor for endometrial carcinoma. LÄS MER
14. Hormones and sex steroid receptors in the female pig : effects of mating, artificial insemination, seminal plasma and genistein
Sammanfattning : Artificial insemination (AI) of sows and gilts is replacing mating in many countries. Another change over the last decades is that soya, rich in phytooestrogens, is routinely used in the diet to pigs. LÄS MER
15. HER2 and TP53 in human breast cancer : studies of methods and prognostic value
Sammanfattning : Prognostic and predictive factors are needed for tailored therapy strategies, aimed at reducing breast cancer relapse and improving survival. The present arsenal of such factors is insufficient. LÄS MER