Sökning: "occludin"
Visar resultat 1 - 5 av 17 avhandlingar innehållade ordet occludin.
1. Coeliac Disease in Childhood : On the Intestinal Mucosa and the Use of Oats
Sammanfattning : Celiaki, eller glutenintolerans, är en av våra vanligaste kroniska sjukdomar i barnaåren. Sjukdomen orsakar en kraftig inflammation i tunntarmens slemhinna efter intag av glutenhaltig föda hos personer med ärftlig benägenhet att utveckla celiaki. En frisk tarm är kraftigt veckad för att öka ytan för upptag av näringsämnen. LÄS MER
2. Cell adhesion proteins in different invasive patterns of colon carcinomas : a morphometric and molecular genetic study
Sammanfattning : Colorectal carcinoma is the second most common type of cancer in both men and women in Sweden. Cancer of the colon and rectum are often considered together and their ten year survival rate is approximately 50 – 60 % depending on sex and location. LÄS MER
3. Protein kinase C-dependent regulation of the epithelial barrier
Sammanfattning : The intestinal epithelium is essential for the absorption of nutrients and for the defence against harmful substances in the gut. The permeability and barrier functions of epithelia are mainly controlled by the intercellular tight junctions. LÄS MER
4. New Approaches to Studies of Paracellular Drug Transport in Intestinal Epithelial Cell Monolayers
Sammanfattning : Studies of intestinal drug permeability have traditionally been performed in the colon-derived Caco-2 cell model. However, the permeability of these cell monolayers resembles that of the colon rather than that of the small intestine, which is the major site of drug absorption following oral administration. LÄS MER
5. Blood Vessels, Biomarkers, and Broken Barriers: lnvestigations of the Brain Vasculature in Models of Neonatal Brain lnjuries
Sammanfattning : Brain injury during the perinatal period can lead to lifelong impairment in cognitive and motor function, or an early death. Term neonatal encephalopathy and preterm germinal matrix haemorrhage are two conditions that can irreversibly injure the brain, but clinical tools for diagnosing and treating these pathologies are lacking. LÄS MER