Sökning: "nya mediciner"
Visar resultat 1 - 5 av 48 avhandlingar innehållade orden nya mediciner.
1. Hip fracture - Mortality and residual lifetime risk of fractures
Sammanfattning : Hip fracture is the most severe clinical manifestation of bone fragility. Hip fracture predominantly affects an already frail population and is associated with multi-cause morbidity and high mortality. Improved knowledge of long-term outcome is essential in order to improve future care and prevention of both fracture and its complications. LÄS MER
2. ROBUST DETECTION AND SPECTRAL ANALYSIS OF SIGNALS WITH APPLICATIONS IN SPECTROSCOPY
Sammanfattning : Modern spectroscopic techniques, such as nuclear quadrupole resonance (NQR), nuclear magnetic resonance (NMR), and Raman spectroscopy, rely heavily on statistical signal processing systems for decision making and information extraction. The first part of this thesis introduces novel robust algorithms for detection, estimation, and classification of signals obtained through these spectroscopic techniques. LÄS MER
3. Pharmacophore Refinement and Lead Optimization - A study of the benzodiazepine site of the GABAA receptors
Sammanfattning : Structure activity relationship studies of synthetic flavone derivatives have been utilized to refine and evaluate a pharmacophore model of the benzodiazepine binding site of the GABAA receptors, originally developed by Zhang et al. (Drug Des. Discovery 1995, 12, 193-248). LÄS MER
4. Costimulation Blockade in Experimental Transplantation
Sammanfattning : Transplantation is the only cure for end-stage organ failure. With the transplantation follows the need for continuous treatment with immunosuppressive agents for as long as the graft functions, which entails major side effects. Less toxic treatments are therefore in great demand. Preferably, the treatment should also be limited in time. LÄS MER
5. Small and Large, Charged Molecules in Solution and at Interfaces
Sammanfattning : The influence of small and large, charged molecules on the properties of aqueous interfaces has important implications in chemistry, biology, and medicine. For example, at the surface of marine aerosols, the presence of halide anions and tropospheric gases gives way to multiphase chemical reactions affecting climate and air quality. LÄS MER