Sökning: "nutrient signalling"

Visar resultat 1 - 5 av 20 avhandlingar innehållade orden nutrient signalling.

  1. 1. Dynamic single-cell modelling of nutrient signalling in budding yeast

    Författare :Sebastian Persson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; nutrient signalling; single-cell; mixed-effects models; stochastic dynamic models; Bayesian inference;

    Sammanfattning : To survive in environments with constantly changing nutrient levels the bud- ding yeast Saccharomyces cerevisiae has a sophisticated nutrient sensing system. A central component of this system is the SNF1 signalling pathway, which primarily helps yeast adapt to glucose limited conditions. LÄS MER

  3. 2. Signalling pathways controlling bacterial adaptation

    Författare :Kristina Jonas; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The conversion of environmental signals into cellular responses is a critically important process that occurs in all organisms. The ability to process information depends, in general, on complex signal transduction and regulatory networks that control genes required to cope with certain environmental conditions. LÄS MER

  4. 3. Lipid Metabolism and Insulin Signalling in Adipocytes : enhanced autophagy in type 2 diabetes

    Författare :Anita Öst; Peter Strålfors; Johanna Gustavsson Dahlberg; Anna Krook; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Energy storage in the adipose tissue, to an extent leading to obesity, is associated with local as well assystemic insulin resistance. When insulin-producing beta-cells in the pancreas gradually fail tocompensate, plasma levels of glucose rise and overt type 2 diabetes is diagnosed. LÄS MER

  5. 4. Salt-inducible kinases in adipose tissue

    Författare :Johanna Sernevi Säll; Proteinfosforylering; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; salt-inducible kinase; SIK; SIK2; fettväv; fettceller; insulinsignalering; glukosupptag; fetma; insulinresistens; salt-inducible kinase; SIK; SIK2; adipose tissue; adipocytes; insulin signalling; glucose uptake; obesity; insulin resistance;

    Sammanfattning : Obesity, insulin resistance and type 2 diabetes (T2D) are metabolic diseases that increase rapidly in the modern society. The underlying mechanisms are complex and involve both environmental and genetic factors. Adipose tissue is an important organ for maintaining whole body energy homeostasis. LÄS MER

  7. 5. Osmoregulation at different stages of the yeast life cycle

    Författare :Cecilia Geijer; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; stress signalling; osmoregulation; aquaporins; cerevisiae; germination; germination;

    Sammanfattning : The ability to adapt to changing and potentially harmful conditions in the surrounding environment is crucial for fitness and survival of all living cells; in particular unicellular organisms, since they are frequently exposed to stress factors such as heat, drought, nutritional starvation and toxic substances. The aim of this thesis is to determine how cells respond to osmotic and nutritional changes in the environment and how downstream targets of signalling cascades are regulated. LÄS MER