Sökning: "nude mice"

Visar resultat 11 - 15 av 63 avhandlingar innehållade orden nude mice.

  1. 11. Cyclooxygenase activity and tumor progression

    Författare :Christian Cahlin; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cyclooxugenase; PGE2; inflammation; cytokine; nitric oxide; indomethacin; IL-6;

    Sammanfattning : Invasive growth of malignant tumors is associated with local and systemic inflammation, which may promote progression and metastases. Inflammation is also responsible for appearing manifestations of advanced cancer as fatigue, anorexia and wasting with eicosanoids, proinflammatory cytokines and nitric oxide as mediators. LÄS MER

  3. 12. Neogenesis and alloxan toxicity in pancreatic islets, with special reference to the transplanted human β-cell

    Författare :Björn Tyrberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Alloxan; β-cell; diabetes; differentiation; growth; insulin secretion; nephrectomy; ob ob; pancreatic islet; transplantation; guinea-pig human; mouse; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : The aim of this work was to study whether adult human pancreatic β-cells have the capacity to proliferate in culture and after transplantation to the renal subcapsular space of mice. An immunosuppressive regimen for human islet discordant xenotransplantation to mice was designed. LÄS MER

  4. 13. Heavy metal-induced activation of the murine immune system and autoimmunity : a comparative study of mercury and silver

    Författare :Uno Johansson; Klas Nordlind; Östergötlands Läns Landsting; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The activation and proliferation ofT- and B-cells induced by treatment with mercuric chloride (HgC12) or silver·nitrate (AgN03) was studied in mouse strains genetically susceptible (SJL, A. SW, A.TH, BALE/C) or resistant (A.TL, BALB. LÄS MER

  5. 14. Evaluation of Alginate Microcapsules for Use in Transplantation of Islets of Langerhans

    Författare :Aileen King; Simon Howell; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Alginate; biocompatibility; cytokines; epimerases; islet transplantation; microencapsulation; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : Transplantation of islets of Langerhans is a potential treatment of type 1 diabetes that aims to restore normal glucose homeostasis. Microencapsulation of islets could enable transplantation in the absence of immunosuppression, which would be beneficial as the side effects associated with immunosuppression outweigh the potential benefits of islet transplantation. LÄS MER

  7. 15. Radioimmunotherapy of experimental ovarian cancer with Astatine-211. An in vivo model for consolidation treatment in women

    Författare :Håkan Andersson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Astatine-211; consolidating treatment; in vitro effects; monoclonal antaibodies; Mov18; ovarian cancer; radioimmunotherapy;

    Sammanfattning : About 850 new cases of ovarian cancer are diagnosed in Sweden every year. In 75 % of the patients the tumour has spread outside the ovaries. The standard treatment is surgery followed by six courses of combination chemotherapy. In spite of a very high frequency of clinical complete responses the 5-year survival is not satisfactory. LÄS MER