Sökning: "nucleoporin"

Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet nucleoporin.

  1. 1. Nucleoporins and Protein Transport in Drosophila

    Författare :Peggy Roth; Christos Samakovlis; Volker Cordes; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; NPC; Nucleoporin; Nup88; Nup214; CRM1; Dorsal; Drosophila; Developmental biology; Utvecklingsbiologi;

    Sammanfattning : Many biological responses rely on the selective translocation of transcriptional regulators in and out of the nucleus through nuclear pore complexes (NPC). More than one million macromolecules per minute pass through the NPC and an important challenge is to understand the coordination of nucleocytoplasmic trafficking. LÄS MER

  2. 2. The evolution of the nuclear envelope

    Författare :Nadja Neumann; Anthony Poole; Gáspár Jékely; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Nuclear pore complex; bouquet; meiosis; nucleus; eukaryote evolution; nucleoporin; tree of life; stem group; recombination; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The nucleus is one of the defining features of eukaryotes and the question of its origin is intimately linked to the evolution of the eukaryotic cell. It is delimited by a double lipid bilayer called the nuclear envelope, which separates the nuclear interior from the cytoplasm. LÄS MER

  3. 3. Disassembly and reassembly of the nuclear pore complex

    Författare :Evgeny A. Onischenko; Einar Hallberg; Paul R. Clarke; Evgeny Onischenko; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : The nuclear pore complexes (NPCs) are multiprotein communicative channels spanning the nuclear envelope. In higher eukaryotes NPCs reversibly disassemble during mitosis into distinct nucleoporin subcomplexes. Some cell types (e.g. LÄS MER

  4. 4. Functional study of Nucleoporins Nup88 and Nup214 during Drosophila Development

    Författare :Nikos Xylourgidis; Christos Samakovlis; Valerie Doye; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; mbo; Nup88; CAN; Nup214; NPC; CRM1; embargoed; NF-kB; REL; Dorsal; Dif; Drosophila; Developmental biology; Utvecklingsbiologi;

    Sammanfattning : More than a million macromolecules per minute pass through the nuclear envelope of a eukaryotic cell. An important challenge is to understand how the NPC coordinate efficiently the bi-directional trafficking necessary for the basal cellular activities and the rapid translocation of regulatory proteins in response to signaling. LÄS MER

  5. 5. Molecular and ultrastructural analysis of Tpr, a nuclear pore complex-attached coiled-coil protein

    Författare :Manuela Hase; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Anchored in the nuclear envelope, nuclear pore complexes (NPCs) are large multiprotein complexes which serve as the gateway for nucleocytoplasmic transport. In vertebrates, a 267kDa protein termed Tpr has been localized to the nucleoplasmic side of the NPCs. The function of Tpr has remained largely elusive. LÄS MER