Sökning: "nucleophilic aromatic substitution"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden nucleophilic aromatic substitution.

  1. 1. Palladium-Catalyzed Nucleophilic Substitution of Alcohols : Mechanistic Studies and Synthetic Applications

    Författare :Supaporn Sawadjoon; Joseph Samec; Takao Ikariya; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; palladium; nucleophilic substitution; mechanism; Organic Chemistry; Organisk kemi;

    Sammanfattning : This thesis deals with the palladium-catalyzed nucleophilic substitution of π-activated alcohols in which the C–O bond of a non-manipulated hydroxyl group is cleaved. The thesis is divided in two chapters describing two different catalytic systems. LÄS MER

  3. 2. Arene Iron Complexes in Organic Synthesis. New Routes to Benzophenones, Diaryl Selenides, Xanthones and Thioxanthones

    Författare :J Peter Storm; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Directed remote Metalation; nucleophilic aromatic addition; nucleophilic aromatic substitution; Arene-iron complexes; balanol; Organic chemistry; Organisk kemi;

    Sammanfattning : A multi-step route to unsymmetrically substituted benzophenones based on cationic hapto6-arene-hapto5-cyclopentadienyl iron complexes has been developed. The key features are nucleophilic aromatic substitution reactions performed on hapto6-2-chlorocarbomethoxybenzene-hapto5-cyclopentadienyl iron hexafluorophosphate with phenoxides, followed by intramolecular Friedel-Crafts ring-closure. LÄS MER

  4. 3. Quantum Chemical Studies of Aromatic Substitution Reactions

    Författare :Magnus Liljenberg; Tore Brinck; Leif Eriksson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Teoretisk kemi och biologi; Theoretical Chemistry and Biology;

    Sammanfattning : In this thesis, density functional theory (DFT) is used to investigate the mechanisms and reactivities of electrophilic and nucleophilic aromatic substitution reactions (SEAr and SNAr respectively). For SEAr, the σ-complex intermediate is preceded by one (halogenation) or two (nitration) π-complex intermediates. LÄS MER

  5. 4. Naphthoxylosides Investigations into glycosaminoglycan biosynthesis

    Författare :Mårten Jacobsson; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organisk kemi; proteoglycan; Organic chemistry; nucleophilic aromatic substitution; thioether; glycosaminoglycan; xylosides; naphthoxylosides;

    Sammanfattning : Glycosaminoglycans (GAGs) are members of a family of polysaccharide structures consisting mostly of repeating disaccharide units. Most GAGs are attached to specific serine residues in proteins to form proteoglycans (PGs). LÄS MER

  7. 5. Perfluroaryl azides : Reactivities, Unique Reactions and their Applications in the Synthesis of Theranostic Agents

    Författare :Sheng Xie; Mingdi Yan; Olof Ramström; Stefan Bräse; KTH; []
    Nyckelord :Click Chemistry; Dipolar Cycloaddition; Enamine; Triazoline; Amidine; Aggregation-induced emission; pure nanodrugs; aryl amide; thioacid azide reaction; nucleophilic aromatic substitution; azide-masked fluorophore; nitrene insertion; Kemi; Chemistry;

    Sammanfattning : The work centersaround perfluoroaryl azides (PFAAs), and theirability to undergo certain fast and robusttransformations. The chemistry was furtherappliedfor biomedical applications.The first section focuses on the azide-aldehyde-amine cycloaddition using PFAAs. LÄS MER