Sökning: "nucleic acid capture"

Hittade 3 avhandlingar innehållade orden nucleic acid capture.

  1. 1. Molecular Tools for Nucleic Acid Analysis

    Författare :Deirdre O'Meara; KTH; []
    Nyckelord :nucleic acid capture; modular probes; biosensor; bio-magnetic separation; hepatitis C; sequencing; pyrosequencing; mutation detection; HIV-1; drug resistance; SNP; allele-specific extension; apyrase; genotyping.;

    Sammanfattning : Nucleic acid technology has assumed an essential role invarious areas ofin vitrodiagnostics ranging from infectious diseasediagnosis to human genetics. An important requirement of suchmolecular methods is that they achieve high sensitivity andspecificity with a fast turnaround time in a cost-effectivemanner. LÄS MER

  3. 2. DNA adductomics: Method development and integration in biological effect monitoring

    Författare :Giulia Martella; Elena Gorokhova; Hitesh V. Motwani; Brita Sundelin; Gunnar Boysen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; DNA adducts; Nucleic acids; High-resolution mass spectrometry; Data-independent acquisition; Biological effect monitoring; Environmental contaminants; Biomarkers; Amphipods as sentinel species; Environmental Sciences; miljövetenskap;

    Sammanfattning : Environmental omics can provide informative biomarkers for identifying pathologies or physiological responses to environmental change. Nucleic acid adductomics, one of the newest omics techniques, is particularly well suited for assessing exposure and effects of environmental contaminants because the technique can capture modifications at the (epi)genome level. LÄS MER

  4. 3. Novel microfluidic based sample preparation methods for rapid separation and detection of viable bacteria from blood for sepsis diagnostics

    Författare :Sharath Narayana Iyengar; Aman Russom; Jonas Tegenfeldt; KTH; []
    Nyckelord :microfluidics; Bioteknologi; Biotechnology;

    Sammanfattning : Sepsis is a serious medical condition characterized by a whole-body inflammatory response caused by bloodstream infection. The final stage of sepsis can lead to septic shock, multiple organ failure, and death. In early sepsis, the concentration of bacteria in the bloodstream is typically low, making diagnosis challenging. LÄS MER