Sökning: "nuclear uptake"

Visar resultat 1 - 5 av 112 avhandlingar innehållade orden nuclear uptake.

  1. 1. Nuclear medicine methods in idiopathic Parkinsonism pre- and postsynaptic dopamine SPECT

    Detta är en avhandling från Umeå : Umeå Universitet

    Författare :Susanna Jakobson Mo; Katrine Åhlström Riklund; Anne Larsson Strömvall; Lars Forsgren; Rimma Axelsson; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nuclear medicine; SPECT; 123I-FP-Cit; 123I-IBZM; dopamine; parkinsonism; Parkinson’s disease; multiple system atrophy; progressive supranuclear palsy; Radiology; radiologi;

    Sammanfattning : Background: Single photon emission computed tomography (SPECT) with dopamine transporter (DAT) and dopamine D2 receptor (D2R) ligands can visualise the integrity of the nigrostriatal dopamine system. Parkinson’s disease (PD) and the atypical parkinsonian diseases (APD), progressive supranuclear palsy (PSP) and multiple system atrophy (MSA), have similar symptoms and dopamine depletion, but differ in pharmacological response and prognosis. LÄS MER

  2. 2. Role of nuclear receptors in the regulation of human adipose tissue metabolism

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Prasad G. Kamble; Jan W Eriksson; Ingrid Dahlman; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human adipose tissue; nuclear receptors; glucocorticoids; estrogen; PPARγ; lipocalin 2; glucose uptake; lipolysis; adipogenesis; genotype-based recall;

    Sammanfattning : Nuclear receptors modulate expression of genes involved in adipose tissue (AT) metabolism. Their improved understanding may provide new treatment options for metabolic disorders such as obesity, insulin resistance (IR) and type 2 diabetes (T2D). LÄS MER

  3. 3. Quantification Methods for Clinical Studies in Nuclear Medicine - Applications in AMS, PET/CT and SPECT/CT

    Detta är en avhandling från Lund University, dept. of Medical Radiation Physics

    Författare :Marie Sydoff; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nuclear Medicine; AMS; PET CT; SPECT CT; dosimetry; internal dosimetry; quantification; activity quantification; volume delineation; radiation; biokinetics; pharmacokinetics; biodistribution;

    Sammanfattning : An essential part of the development of new radiopharmaceuticals for use in diagnostic nuclear medicine is the determination of its biokinetic properties. The uptake and turn-over of the radiopharmaceutical in the source organs is of great interest since this could determine whether the radiopharmaceutical would be suitable for clinical use or not. LÄS MER

  4. 4. Radioiodine Therapy of Hyperthyroidism - Simplified patient-specific absorbed dose planning

    Detta är en avhandling från Helene Jönsson, Swedish Radiation Protection Authority, SE-171 16 Stockholm, Sweden

    Författare :Helene Jönsson; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiobiologi; Radiofarmaceutisk teknik; Radiopharmaceutical technology; absorbed dose. optimise; hyperthyroidism; therapy; 131-I; radioiodine; Nukleärmedicin; radiobiology; Nuclear medicine;

    Sammanfattning : Radioiodine therapy of hyperthyroidism is the most frequently performed radiopharmaceutical therapy. To calculate the activity of 131-I to be administered for giving a certain absorbed dose to the thyroid, the mass of the thyroid and the individual biokinetic data, normally in the form of uptake and biologic half-time, have to be determined. LÄS MER

  5. 5. Computational patient models for simulation of dynamic gamma-camera imaging : Application to renography and peptide receptor radionuclide therapy

    Detta är en avhandling från Lund University, Faculty of Science, Department of Medical Radiation Physics

    Författare :Gustav Brolin; [2017-09]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nuclear medicine; Gamma camera; Renography; Radionuclide therapy; Internal dosimetry; Pharmacokinetics;

    Sammanfattning : Many nuclear medicine investigations rely on gamma-camera imaging to study and quantify the distribution of radiopharmaceuticals or radionuclides in the patient as a function of time. This is typically used for diagnostic studies of physiological functions or for calculation of absorbed doses following radionuclide therapy. LÄS MER