Sökning: "nuclear magnetic resonance NMR"
Visar resultat 1 - 5 av 213 avhandlingar innehållade orden nuclear magnetic resonance NMR.
1. Nuclear Magnetic Relaxation in Micellar Solution and Lyotropic Liquid Crystals. Tools and Applications
Sammanfattning : Structurally, this Thesis is divided into two parts thatdescribe (i) the hardware development for NMR relaxationstudies and (ii) its applications for studies of the surfactantsystems.The developed hardware solutions allow to expand thefrequency range covered by conventional NMR spectrometers tomake NMR experiments feasible at resonance frequencies down to100 kHz. LÄS MER
2. Characterizing Chromatography Media : NMR-based Approaches
Sammanfattning : Liquid chromatography is an essential technique in manufacturing biopharmaceuticals where it is used on all scales from analytical applications in R&D to full-scale production. In chromatography the target molecule, typically a protein, is separated and purified from other components and contaminants. LÄS MER
3. Development and applications of NMR relaxation methods to study protein and ligand dynamics
Sammanfattning : This thesis involves the study of proteins. These molecules exist in many variants, and perform most of our bodily functions. This includes signaling (for example the presence of capsaicin, which makes food spicy), molecular transport (including oxygen), catalysis (including food digestion) and part of our body structure (such as muscles). LÄS MER
4. Molecular recognition and dynamics in proteins studied by NMR
Sammanfattning : Knowledge of dynamics in protein is very important in the description of protein function and molecular recognition. The thesis investigates protein dynamics on time-scales from milli- to sub-nanosecond, with focus on the latter, using NMR spin relaxation experiments on two proteins, the 138-residue carbohydrate recognition domain of galectin-3 (Gal3C) and the 56-residue B1 domain of bacterial protein G (PGB1). LÄS MER
5. NMR Imaging of Flow and Perfusion using Hyperpolarized Nuclei: Theoretical Considerations and Application to Experimental Models
Sammanfattning : In the studies presented in this thesis, hyperpolarized tracers have been used for the study of macroscopic flow and capillary perfusion with magnetic resonance imaging. The feasibility of performing vascular studies using echo-planar imaging (EPI) and hyperpolarized 129Xe was investigated using xenon dissolved in ethanol prior to injection into a flow phantom. LÄS MER