Sökning: "nuclear atypia"
Hittade 5 avhandlingar innehållade orden nuclear atypia.
1. Chromosomal Instability and Genomic Amplification in Bone and Soft Tissue Tumours
Sammanfattning : Acquired genetic abnormalities are found in all types of malignant tumours and may contribute to neoplastic processes by altering protein structure or dosage. Many bone and soft tissue tumours (BSTT) are characterised by complex patterns of chromosome changes, including extensive intratumour heterogeneity and amplification of DNA sequences. LÄS MER
2. On the prognosis and treatment of early stage endometrial carcinoma : Studies with special reference to uterine papillary serous carcinoma
Sammanfattning : The prognosis and therapy in the subgroup of endometrial malignancies called Uterine Papillary Serous Carcinoma (UPSC) was investigated. This entity constitutes about 6-8 % of all endometrial carcinomas clinical stage I but, as has been shown here, accounts for one third of the cancer mortality in the early stages of endometrial carcinoma. LÄS MER
3. INFLAMMATION AND PROSTATIC CARCINOGENESIS ? A MORPHOLOGICAL STUDY OF THE HUMAN PROSTATE
Sammanfattning : ABSTRACT: Chronic inflammation has been suggested to be linked to cancers. Inflammatory infiltrates are often found in and around foci of prostatic atrophy. These foci, called proliferative inflammatory atrophy (PIA), are proposed as precursors of prostate cancer (PCa) or prostatic intraepithelial neoplasia (PIN). LÄS MER
4. Ploidy, cell proliferation and apoptosis in lymphoid malignancies : methodological and clinical aspects
Sammanfattning : The DNA aneuploidy and proliferative activity have been previously shown to carry a clinical significance in Iymphoid malignancies. However, the application of these parameters is complicated by methodological difficulties. LÄS MER
5. A study of the transition from premalignancy to clinical prostate cancer
Sammanfattning : Prostate cancer remains the most commonly diagnosed life-threatening malignancy and the second leading cause of death from cancer in men. However, little is known about molecular mechanisms that underline its initiation and progression. LÄS MER