Sökning: "normal tissue response"
Visar resultat 21 - 25 av 322 avhandlingar innehållade orden normal tissue response.
21. Determination and use of radiobiological response parameters in radiation therapy optimization
Sammanfattning : Optimization of radiation therapy is critically dependent on the use of patient related information. For this reason, radiobiological models describing the dependence of tumour and normal tissue responses on the irradiated volume and the dose-time-fractionation schedule should be introduced. LÄS MER
22. New models for relapsing polychondritis and rheumatoid arthritis : focus on the tissue specific immune response
Sammanfattning : Relapsing polychondritis (RP) and rheumatoid arthritis (RA) are autoimmune diseases where an inappropriate immune response destroys cartilage. In RP, the ears, larynx, nose and joints are affected, while the most prominent sign of RA is arthritis. LÄS MER
23. The mucosal immune response against Helicobacter pylori infection
Sammanfattning : H. pylori infection affects more than half of the world’s population. The clinical consequences range from asymptomatic gastritis to peptic ulceration and gastric malignancy. H. LÄS MER
24. Mesenchymal niche contribution to normal and malignant hematopoiesis
Sammanfattning : Normal hematopoiesis is tightly regulated by hematopoietic microenvironment/niche in bone marrow (BM) via direct hematopoietic cell-niche cell interaction and factors secreted by various types of cellular niches. The BM niche consists of cells of mesenchymal cell origin including mesenchymal stem cells (MSCs) and progenitor cells (MPCs). LÄS MER
25. Altering Radiation Response with Time, Volume and Fractionation
Sammanfattning : Radioresistance, the failure to achieve a desired outcome, is an obstacle in clinical radiotherapy. In this thesis we investigate factors affecting radioresistance and strategies to overcome it, both with established clinical approaches and by using novel pre-clinical discoveries. LÄS MER