Sökning: "nondisjunction"

Hittade 2 avhandlingar innehållade ordet nondisjunction.

1. 1. Mitotic failure and genome stability in benign, premalignant and malignant human tissues

   Författare :Rüdiger G Steinbeck; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :aneuploidy; CDF; clonal selection; DNA content; image microphotometry; interphase; microsection; nondisjunction; unbalanced telophase;

   Sammanfattning : Mitotic failure may occur throughout the human lifespan. Individual nuclear mistakes will escape detection within the mass of somatic cells. The probability of nondetection increases with progression in development. LÄS MER

3. 2. Proteins influencing the integrity of meiotic chromosome dynamics

   Författare :Mary-Rose Hoja; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Aneuploidy (trisomy or monosomy) is the leading genetic cause of human pregnancy loss and results from aberrant meiotic chromosome segregation. Accurate segregation of meiotic chromosomes depends on extensive pairing (called synapsis) and recombination between them. LÄS MER