Sökning: "non-linear modelling"

Visar resultat 11 - 15 av 186 avhandlingar innehållade orden non-linear modelling.

1. 11. Moisture Transport in Porous Media. Modelling Based on Kirchhoff Potentials

   Författare :Jesper Arfvidsson; Avdelningen för Byggnadsfysik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; moisture distribtion; wood drying; wood; diffusion coefficient; numerical modelling; moisture flow; Moisture; transient measurements; periodic boundary condition; penetration depth; sorption coefficient; non-linear moisture flow; calculation model; anisitropy; Kirchhoff potentials; evaluation; moisture transport; Building construction; Byggnadsteknik;

   Sammanfattning : The work presented in this thesis is focused on the development of the new concept to describe isothermal moisture transport using Kirchhoff potentials. The first four papers deal with moisture transport in porous media using Kirchhoff potentials. The last three papers deal with wood. LÄS MER

3. 12. Pharmacometrics to characterize innate immune response and antibacterial treatments

   Författare :Anders Thorsted; Lena E. Friberg; Elisabet I. Nielsen; Mats O. Karlsson; Gauri G. Rao; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacometrics; non-linear mixed effects modelling; modelling; pharmacokinetics; pharmacodynamics; pkpd; antibiotics; cefuroxime; piperacillin; phagocytes; lipopolysaccharide; endotoxin; porcine endotoxemia; challenge studies; sepsis; critically ill; Farmaceutisk vetenskap; Pharmaceutical Science;

   Sammanfattning : The immune system protects the host against pathogens by distinguishing self from non-self. However, it is most-often disregarded in pharmacokinetic-pharmacodynamic (PKPD) characterization of (new and old) antibiotics. LÄS MER

4. 13. Pharmacometric Investigations of Prediction Precision and Advances of Models for Composite Scale Data

   Författare :Gustaf Wellhagen; Maria C. Kjellsson; Bengt Hamrén; Per Olsson Gisleskog; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacometrics; modelling; non-linear mixed effects modelling; composite scale data; total score data; total score analysis; precision prediction; bounded integer; bounded integer model; IRT-informed total score analysis; item response theory-informed; mixed models for repeated measures; MMRM; dose-response; dose-response mixed models for repeated measures; DR-MMRM; HbA1c models; fit-for-purpose analysis; clinical trial analysis; Farmaceutisk vetenskap; Pharmaceutical Science;

   Sammanfattning : Clinical trials are needed to evaluate new treatments. In late-stage clinical trials, failures are mostly due to lack of efficacy. Fit-for-purpose analysis methods will likely increase the success rates and advance drug development by providing higher precision to support decisions such as go/no-go, dose selection, or sample size. LÄS MER

5. 14. RoPax Ship Collision – a Methodology for Survivability Analysis

   Författare :Per Hogström; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; non-linear FEA; failure modelling; uncertainty analysis; Crashworthiness; sheet metal failure; ship collision; damage stability;

   Sammanfattning : Throughout the world, ships are continuously being declared as total losses and 10 to 15% of these accidents are collisions between ships. The consequences of a collision are diverse and depend on the ship type, e.g. oil outflow in the case of damaged tankers or loss of stability in damaged passenger ships. LÄS MER

7. 15. Holistic Assessment of Survival Time after Ship Collision

   Författare :Per Hogström; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; non-linear FEA; failure modelling; ship collision; sheet metal failure; uncertainty analysis; Damage stability;

   Sammanfattning : Collisions between ships contribute to ship losses even in modern time, and the International Maritime Organization (IMO) strives towards a more risk-based view on addressing the damage stability of ships. This thesis presents a holistic methodology for computing the consequences of ship collisions. LÄS MER