Sökning: "non-esterified fatty acids"
Visar resultat 1 - 5 av 13 avhandlingar innehållade orden non-esterified fatty acids.
1. Fatty acids induce potentially atherogenic changes in extracellular matrix proteoglycans
Sammanfattning : Insulin resistance and type 2 diabetes (T2D) are associated with an increased prevalence of atherosclerotic cardiovascular disease (CVD). A key step in the initiation of atherogenesis is retention of low density lipoproteins (LDL) in the intima by chondroitin sulfate (CS)-rich proteoglycans (PG). LÄS MER
2. Modelling of tolerance and rebound in normal and diseased rats
Sammanfattning : The development of rebound and tolerance is an important consideration when optimizing medical therapy, both with respect to drug dosing and adverse effects. By using quantitative approaches to study these processes, potential risks can be minimized. LÄS MER
3. Molecular cloning and characterization of the murine acyl-CoA thioesterase CTE-I
Sammanfattning : Mouse cytosolic type I acyl-CoA thioesterase (CTE-I) is a member of the type I family of acylCoA thioesterases. These enzymes hydrolyze acyl-CoAs to non-esterified fatty acids (NEFAs) and Coenzyme A (CoA-SH) and are strongly induced in rodent liver by a diverse group of compounds called peroxisome proliferators. LÄS MER
4. Perilipin expression in the islets of Langerhans and Surface expression in the baculovirus/insect cell system
Sammanfattning : Surface display in insect cells: Systems available for surface display that utilize bacterial phages are insufficient for displaying a number of eukaryotic proteins. By instead presenting proteins on the surface of eukaryotic cells or virus, some of these problems might be overcome. LÄS MER
5. Peroxisomal and mitochondrial enzymes involved in lipid metabolism : studies on function and regulation
Sammanfattning : Fatty acids constitute a major part of the energy that we obtain from the diet and are also the principal source for mammals to store energy. To use the incoming or stored fatty acids as energy, the fatty acids needs to be metabolized of which the majority of fatty acids will be degraded by the mitochondrial β-oxidation system that in the end generates energy to the cell in the form of ATP. LÄS MER