Sökning: "nodose ganglion"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden nodose ganglion.

  1. 1. Regeneration of Peripheral Nerves. The role of protein kinases, with emphasis on neurotrophic factor stimulation

    Författare :Peter Wiklund; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NT-4; NT-3; NGF; MAPK; PKG; PKA; PKC; nodose ganglion; DRG; conditioning effect; neurotrophic factors; protein kinases; peripheral; nerve regeneration; BDNF; GDNF; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : The purpose of this study was to investigate the role of protein kinases in peripheral nerve regeneration, with the use of dorsal root ganglia (DRG) and nodose ganglia explants from adult mice. The effects of neurotrophic factor stimulation and protein kinase inhibition were studied for long (days) and short term (minutes) effects. LÄS MER

  3. 2. Neuropeptide circuitries regulating food and water intake

    Författare :Christian Broberger; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :agouti gene-related protein; anorexia mutation; arcuate nucleus; cholecystokinin; cocaine- and amphetamine-regulated transcript; coexistence; confocal microscopy; dorsal root ganglion; feeding; hypocretin; immunohistochemistry; in situ hybridization; melanin-concentrating hormone; nodose ganglion; nucleus tractus solitaxii; orexin; paraventricular nucleus; satiety; sensory neurones; pro-opiomelanocortin; vagus nerve;

    Sammanfattning : An adequate supply of nutrients through food intake is critical for survival, as evidenced by disorders such as obesity and anorexia, which in the long run may be life-threatening. Feeding behaviour is ultimately controlled by interacting neuronal populations in the brain. LÄS MER

  4. 3. Regulation of signaling molecules in sensory neurons and spinal cord : studies on nerve injury models and transgenic mice

    Författare :Tie-Jun Shi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Behaviour; cell loss; dorsal root ganglion; immunohistochemistry; in situ hybridization; mRNA; nerve injury; neuropathic pain; neuropeptides; nociception; primary sensory neuron; spinal cord.;

    Sammanfattning : Nerve injury may cause neuropathic pain in patients. Similar symptoms can also be seen in some animal models. LÄS MER

  5. 4. Studies of cytokine mediated regulation of central nervous functions : role of prostaglandins

    Författare :Monica Ek; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :interleukin-1; prostaglandin E2; central nervous system; HPA axis; fever; vagus nerve;

    Sammanfattning : The communication between the immune system and the central nervous system (CNS) results in an array of centrally regulated illness responses, including fever and increased hypothalamus-pituitary-adrenal (HPA) axis activity. The mechanisms by which the immune system signals the brain across the blood-brain barrier have not been completely elucidated, but proinflammatory cytokines, like interleukin-1 (IL-1), are believed to act as important mediators. LÄS MER

  7. 5. Structure and expression of the TP and EP1 prostanoid receptor genes

    Författare :Björn Båtshake; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; Neurologi; neurofysiologi; Neurology; neuropsychology; neurophysiology;

    Sammanfattning : Prostanoids are ubiquitously distributed lipid signaling molecules derived from arachidonic acid, that exhibit numerous and diverse biological effects in a variety of physiological and pathophysiological conditions. The cell surface receptors for the prostanoids belong to the family of G protein-coupled receptors. LÄS MER