Sökning: "node affinity"
Visar resultat 1 - 5 av 9 avhandlingar innehållade orden node affinity.
1. Software Techniques for Distributed Shared Memory
Sammanfattning : In large multiprocessors, the access to shared memory is often nonuniform, and may vary as much as ten times for some distributed shared-memory architectures (DSMs). This dissertation identifies another important nonuniform property of DSM systems: nonuniform communication architecture, NUCA. LÄS MER
2. Immunoglobulin gene usage and affinity maturation in antiviral antibodies
Sammanfattning : The ability of antibodies to block infections makes them highly relevant for successful vaccine development. Through the papers described in this thesis, I attempt to characterize the functional and genetic aspects of antiviral antibodies induced by infection and vaccination. LÄS MER
3. Antibody based plasma protein profiling
Sammanfattning : This thesis is about protein profiling in serum and plasma using antibody suspension bead arrays for the analysis of biobanked samples and in the context of prostate cancer biomarker discovery. The influence of sample preparation methods on antibody based protein profiles were investigated (Papers I-III) and a prostate cancer candidate biomarker identified and verified (Papers III-V). LÄS MER
4. THE ROLE OF DENDRITIC CELLS AND TYPE I INTERFERON IN THE GENERATION AND FUNCTION OF T FOLLICULAR HELPER CELLS
Sammanfattning : Generation of long-lived plasma cells and memory B cells of high affinity takes place in germinal centers and depends on help from a specialized CD4+ T cell subset termed T follicular helper (Tfh) cells. These processes are crucial for long-term protection upon natural infection or in settings of vaccination, however they are also responsible for development of antibody-mediated autoimmune disease. LÄS MER
5. Acoustofluidic preparation of whole blood components
Sammanfattning : Whole blood is rich in information about the physical state of an individual and is routinely used in a variety of clinical and research applications. In this thesis, the use of a microfluidic technique called acoustophoresis for separation of different blood components is explored. LÄS MER