Sökning: "nmr lock"

Hittade 4 avhandlingar innehållade orden nmr lock.

  1. 1. Nuclear Magnetic Relaxation in Micellar Solution and Lyotropic Liquid Crystals. Tools and Applications

    Författare :Ruslan Sitnikov; KTH; []
    Nyckelord :NMR; NMR relaxation dispersion; NMR spectrometer; low NMR frequencies; NMR duplexer; NMR preamplifier; NMR lock; surfactant systems; micellar solutions; lyotropic liquid crystals; cubic mesophase;

    Sammanfattning : Structurally, this Thesis is divided into two parts thatdescribe (i) the hardware development for NMR relaxationstudies and (ii) its applications for studies of the surfactantsystems.The developed hardware solutions allow to expand thefrequency range covered by conventional NMR spectrometers tomake NMR experiments feasible at resonance frequencies down to100 kHz. LÄS MER

  3. 2. Protein Dynamics Studied by NMR Spin Relaxation. Conformational Transitions of a Calmodulin Mutant

    Författare :Patrik Lundström; Biofysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molekylär biofysik; Molecular biophysics; spin relaxation; rotating-frame; NMR; multiple-quantum; EF-hand; chemical shift; chemical exchange; calcium binding proteins; calmodulin;

    Sammanfattning : Binding of calcium to the protein calmodulin leads to molecular reorganization that enables interaction with target peptides and activation of downstream processes. I have studied the dynamics of the calcium-loaded form of a C-terminal calmodulin mutant (E140Q-Tr2C) using NMR spin relaxation experiments. LÄS MER

  4. 3. Studies of oligosaccharides and carbon-13 enriched bacterial polysaccharides using NMR spectroscopy and computer simulations

    Författare :Alexandra Kjellberg; Steven Homans; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Kemi; Organic Chemistry; organisk kemi;

    Sammanfattning : The conformation and dynamics of the trisaccharide methyl β-D-Glcp-(1--> 2)[β-D-Glcp-(1 --> 3)] α-D-Manp and its constituent disaccharides methyl β-D-Glcp-(1 --> 2) α-D-Manp and methyl β-D-Glcp-(1 --> 3) α-D-Manp have been studied using computer simulations and NMR spectroscopy. The computer simulations applied were Metropolis Monte Carlo simulations employing the HSEA force field and Langevin dynamics simulations using the PARM22 and CHEAT95 force fileds. LÄS MER

  5. 4. Apoptosis Regulation via the Mitochondrial Pathway : Membrane Response upon Apoptotic Stimuli

    Författare :Marc-Antoine Sani; Gerhard Grobner; Antoinette Killian; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Apoptosis; BH4 peptide; Bax-α1 peptide; model membrane; cardiolipin; solid phase peptide synthesis; circular dichroism; solid-state nuclear magnetic resonance spectroscopy.; Biophysics; Biofysik;

    Sammanfattning : The aim of this thesis was the investigation of the mitochondrial response mechanisms upon apoptotic stimuli. The specific objectives were the biophysical characterization of membrane dynamics and the specific roles of lipids in the context of apoptotic regulation occurring at the mitochondrion and its complex membrane systems. LÄS MER