Sökning: "njurar"

Visar resultat 1 - 5 av 38 avhandlingar innehållade ordet njurar.

1. 1. 99mTc-DMSA renal scintigraphy in the diagnosis and follow-up of acute pyelonephritis in children

   Författare :Lena Wallin; Lund Klinisk fysiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tomography; radiology; Clinical physics; progressive renal damage; kidney length; kidney radioactive uptake; pyelonephritis; DMSA-scintigraphy; medical instrumentation; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering;

   Sammanfattning : The aim of the present thesis was to define and evaluate a strategy for identification of children who are at risk of developing progressive renal lesions after acute pyelonephritis. Tc-DMSA renal scintigraphy is widely accepted as the most sensitive method for detecting parenchymal lesions and diagnosing acute pyelonephritis. LÄS MER

3. 2. Long-term outcome of vesicoureteral reflux and reflux nephropathy in adults - clinical and radiological aspects

   Författare :Jan Köhler; Njurmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nefrologi; nephrology; Urology; Adults; antireflux surgery; pregnancy; reflux nephropathy; Urologi; urinary tract infection; vesicoureteral reflux; urography;

   Sammanfattning : The aim was to study the long-term consequencies of vesicoureteral reflux and reflux nephropathy (RN) in adults, with regard to radiological progression, urinary tract infections, renal functional impairment, hypertension, and to determine if the extent of renal damage can predict the outcome. Attempts to differentiate between acquired and developmental renal damage were also made. LÄS MER

4. 3. ADAMTS13 phenotype in health and disease with special reference to thrombotic thrombocytopenic purpura

   Författare :Minola Manea Hedström; Lund Pediatrik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urology; tubular cells; podocytes; kidney; plasma; ADAMTS13; thrombotic thrombocytopenic purpura; nephrology; Urologi; nefrologi; Pediatrics; Pediatri;

   Sammanfattning : Von Willebrand factor (VWF) is synthesized and secreted by endothelial cells into the plasma as a series of multimers. VWF induces the formation of platelet plugs at sites of vascular injury and high shear stress. Biological activity is dependent on multimeric size, which is regulated in plasma by the VWF-cleaving protease ADAMTS13. LÄS MER

5. 4. Studies of EHEC and the complement system in renal diseases

   Författare :Zivile Békassy; Lund Pediatrik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; EHEC; hemolytic uremic syndrome; thrombotic microangiopathy; atypical hemolytic uremic syndrome; alternative pathway of complement; dense deposit disease; eculizumab;

   Sammanfattning : This thesis addressed the diagnosis, pathogenesis and clinical course of specific renal diseases hemolytic uremic syndrome (HUS) and dense deposit disease (DDD). HUS may be associated with infection caused by Enterohemorrhagic Escherichia coli (EHEC) or with complement dysfunction due to complement mutations or auto-antibodies (atypical HUS, aHUS). LÄS MER

7. 5. Structural and Functional Studies of Wilms Tumour Protein - WT1; Novel Insights into Functionality of Zinc Finger Proteins

   Författare :Elmar Nurmemmedov; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Naturvetenskap; Natural science; function; structure; transcription factor; cancer; affinity; kinetics; Biacore; RNA binding; DNA binding; Wilms tumour WT1 ; zinc finger;

   Sammanfattning : The molecular process under which message in DNA is relayed onto RNA is called transcription, and it accomplished through involvement of so-called transcription factors. Zinc finger proteins are one of the most abundant classes of regulatory proteins in eukaryotic cells where they play central roles in a variety of cellular activities. LÄS MER