Sökning: "nitrosative stress"

Hittade 5 avhandlingar innehållade orden nitrosative stress.

  1. 1. Bacterial Adaptive Responses - Coping with Oxygen Limitation, Reactive Nitrogen Species and Disulfide Stress

    Författare :Annika Rogstam; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bacillus subtilis; redox regulation; nitrosative stress; disulfide stress;

    Sammanfattning : Bacteria have a remarkable ability to adapt to different environments. When bacteria encounter stress that causes macromolecular damage in the cell, leading to a suboptimal performance of cell metabolism, they can elicit an adaptive response. LÄS MER

  3. 2. Thioredoxin and glutaredoxin systems under oxidative and nitrosative stress

    Författare :Xiaoyuan Ren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Our knowledge about reactive oxygen species (ROS) and reactive nitrogen species (RNS) has been changed from simple damaging molecules to redox signaling mediators. ROS/RNS mediated signaling is mainly based on the reversible post-translational modifications of cysteine which works as a switch for protein functions. LÄS MER

  4. 3. Vitreoscilla Haemoglobin - Peroxidase Activity and Metabolic Aspects

    Författare :Malin Kvist; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; metabolism; Biokemi; Metabolism; Biochemistry; Naturvetenskap; Natural science; lipid peroxidation; hypoxia; salt stress; Escherichia coli; Lactococcus lactis; hydrogen-bonding network; proximal site; mutations; Vitreoscilla haemoglobin; peroxidase activity; Proteins; enzymology; Proteiner; enzymologi;

    Sammanfattning : The function of non-vertebrate haemoglobins (Hbs) appears more diverse than that of vertebrate Hbs, possibly reflecting the various demands to be met among their hosts. Sharing structural features with other haem proteins/enzymes, Hbs display a qualitative overlap in activities with functions extending beyond oxygen transport/storage. LÄS MER

  5. 4. Cerebral Protection in Experimental Cardiopulmonary Resuscitation : With Special Reference to the Effects of Methylene Blue

    Författare :Adriana Miclescu; Lars Wiklund; Samar Basu; Jo Kramer-Johansen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiac arrest; cardiopulmonary resuscitation; reperfusion injury; methylene blue; nitric oxide; nitric oxide synthases; blood-brain barrier; Anaesthetics and intensive care; Anestesiologi och intensivvård; Anestesiologi; Anaesthesiology;

    Sammanfattning : Although survival rates are increasing, brain injury continues to be a leading cause of death after cardiac arrest (CA). Permanent brain damage after CA is determined by limited tolerance to ischemia from CA and cardiopulmonary resuscitation (CPR), as well as the unique cerebral response to reperfusion after return of spontaneous circulation (ROSC). LÄS MER

  7. 5. Function, expression and polymorphism of human alcohol dehydrogenase 3/glutathionedependent formaldehyde dehydrogenase

    Författare :Jesper Hedberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Alcohol dehydrogenase 3 (ADH3), identical to glutathione-dependent formaldehyde dehydrogenase, plays a vital role in the defense against formaldehyde through the activity for the spontaneously formed adduct between formaldehyde and glutathione, Shydroxymethylglutathione (HMGSH). ADH3 may also participate in the metabolism of Snitrosylated glutathione, GSNO. LÄS MER