Sökning: "nitrite"

Visar resultat 16 - 20 av 112 avhandlingar innehållade ordet nitrite.

  1. 16. Nitric oxide generation from nitroglycerin and other no-donors measured in the lung and studies on nitrate tolerance in the cardiovascular system

    Författare :Per Agvald; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Exhaled; nitric oxide; nitroglycerin; nitrite; temperature; tolerance; hypoxia;

    Sammanfattning : Nitroglycerin (GTN) and compounds referred to as nitrovasodilators or NOdonors are frequently used in the treatment of ischemic heart disease. The common mode of action for these drugs is liberation of nitric oxide (NO). Nitric oxide evokes relaxation of smooth muscle through activation of guanylate cyclase with subsequent formation of eGMP. LÄS MER

  3. 17. Oropharyngeal origin of markers in exhaled breath

    Författare :Helena Marteus; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Exhaled nitric oxide; exhaled breath condensate; saliva; nitrite; nitrate; ammonia; pH; bacteria;

    Sammanfattning : Normal NO formation in the human airways occurs primarily in the nasal airways, where it is catalyzed by inducible NO synthase (iNOS), and in the oropharyngeal tract, via as yet not fully defined pathways. This NO can be detected in exhaled breath and when inflammation is present in the airways, for example in asthma, the concentration of NO is increased. LÄS MER

  4. 18. Influence of the microflora on gastrointestinal nitric oxide generation : studies in newborn infants and germ-free animals

    Författare :Tanja Sobko; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Nitrite; nitrate; IBD; lactobacilli; probiotics; germ-free; SCFA; H 2; newborn infants;

    Sammanfattning : Interactions between intestinal bacteria and the host play an important role in physiological regulation of gut function and in development of various diseases. Nitric oxide (NO) exhibits a variety of biological actions in the gut including regulation of regional blood flow, gut motility, water and electrolyte transport and immunity. LÄS MER

  5. 19. Formation and role of nitric oxide in host defense reactions in the urinary bladder

    Författare :Edward R I Morcos; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :bladder cancer; BCG; cytokines; urinary tract infection; nitric oxide; nitric oxide synthase; nitrite; nitrate; capillary electrophoresis;

    Sammanfattning : Nitric oxide (NO) is an important biological mediator and cell signaling molecule. It is also involved in several host defense reactions. NO is formed in vivo from L-arginine by the enzyme NO synthase (NOS). However, it can also be formed non-enzymatically from acidified nitrite. LÄS MER

  7. 20. Experimental skin flaps and nitric oxide

    Författare :Örjan Gribbe; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Surgical flaps; nitric oxide; ischemia; reperfusion; nitrite; laser Doppler; transit-time ultrasound flowmetry; electron microscopy; NO donors; NOS inhibitors;

    Sammanfattning : Surgical flaps are used in plastic surgery to reconstruct tissue defects due to trauma or cancer removal. Occasionally flaps are subjected to ischemia and reperfusion injury leading to flap failure. LÄS MER