Sökning: "nitric oxide synthase"

Visar resultat 16 - 20 av 189 avhandlingar innehållade orden nitric oxide synthase.

1. 16. Post-Transcriptional Regulation of the Murine Inducible Nitric Oxide Synthase Gene

   Författare :Malin Söderberg; Matti A. Lang; Françoise Raffalli-Mathieu; Eeva Moilanen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biochemistry; iNOS; inducible nitric oxide synthase; gene regulation; post-transcriptional; mRNA stability; RNA-protein interactions; dexamethasone; murine; heterogeneous nuclear ribonucleoprotein; hnRNPI; hnRNPL; Farmaceutisk biokemi; Pharmaceutical biochemistry; Farmaceutisk biokemi;

   Sammanfattning : Large amounts of nitric oxide (NO) are produced by the inducible nitric oxide synthase (iNOS) upon inflammatory stimuli. NO is a multifaceted molecule, which may have beneficial effects as an antimicrobial agent in the immune defense, or cytotoxic effects in chronic inflammations, manifested as e.g. arthritis and asthma. LÄS MER

3. 17. Nitric oxide in brain contusion

   Författare :Caroline Gahm; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Apoptosis; Colchicine; Dexamethasone; eNOS; human; immunohistochemistry; iNOS; L-NAME; L-NIL; neuronal degeneration; Nimodipine; nitric oxide; NO; nNOS; rat; SPBN; Tirilazad Mesylate; traumatic brain injury;

   Sammanfattning : Trauma to the brain is a leading cause of death and disability. The primary injury initiates a cascade of biochemical reactions in the brain that causes further neuronal damage, a process referred to as secondary brain injury. LÄS MER

4. 18. Nitric oxide synthase in female reproductive and urinary organs: Hormonal regulation and functional significance

   Författare :Jassim Al-Hijji; Lund Obstetrik och gynekologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gynaecology; Obstetrics; estrogen; trophoblast; placenta; vagina; Nitric oxide; uterus; ovarian steroids; andrology; reproduction; sexuality; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet;

   Sammanfattning : Nitric oxide synthase (NOS) activity was studied in cytosolic and particulate fractions in reproductive organs from rabbit (uterus and vagina) and rat (uterus, vagina and cervix). NOS was found predominantly in cytosolic fractions in all tissues and the activity of NOS in both fractions was highly Ca2+ dependent. LÄS MER

5. 19. Nitric oxide modulates neutrophil function

   Författare :Tony Forslund; Per Venge; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : An important role of the neutrophils is to attack and destroy microbial intruders. In order to do so, these leukocytes must adhere to the blood vessel wall, pass through the endothelial cell layer, move through the tissues to the point of infection, ingest the intruder and destroy it. LÄS MER

7. 20. Gastrointestinal mucosal protective mechanisms : Mudolatory effects of Heliobacter pyroli on the gastric mucus gel barrier and mucosal blood flow in vivo

   Författare :Christer Atuma; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; mucus gel layer; mucosal blood flow; mucus thickness; chronic infection; rat; platelet activating factor; mast cell; nitric oxide; nitric oxide synthase; ketotifen; intra-vital microscopy; microelectrode; laser-Doppler flowmetry; L-NNA; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

   Sammanfattning : The gastrointestinal mucus gel layer and blood flow are two important mechanisms for protection at the pre-epithelial and sub-epithelial levels, respectively. Helicobacter pylori might circumvent these mechanisms and elicit a chronic inflammatory response with consequent ulcers in the stomach and duodenum. LÄS MER