Sökning: "nicotinic acid"

Visar resultat 16 - 20 av 25 avhandlingar innehållade orden nicotinic acid.

1. 16. Regulation of Duodenal Mucosal Barrier Function and Motility : The Impact of Melatonin

   Författare :Anna Sommansson; Markus Sjöblom; Olof Nylander; Oliver Bachmann; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 51Cr-EDTA; bicarbonate secretion; duodenum; enteric nervous system; enterochromaffin cell; ethanol; hexamethonium; in vivo; mecamylamine; motility; mucosal permeability; parecoxib; rat; Physiology; Fysiologi;

   Sammanfattning : The duodenal mucosa is regularly exposed to acid, digestive enzymes and ingested noxious agents. It is thus critical to maintain a protective barrier to prevent the development of mucosal injury and inflammation, which are often observed in situations when barrier function is impaired. LÄS MER

3. 17. Translational accuracy, ribozyme efficiency and NAD metabolism in Escherichia coli

   Författare :Martin Stancek; Leif Isaksson; Lars Hederstedt; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Escherichia coli; translational accuracy; nicotinate mononucleotide adenylyltransferase; Microbiology; Mikrobiologi;

   Sammanfattning : Interactions between the translational machinery and mRNA in Escherichia coli have been studied. In the first section nonsense codon readthrough and changed translational reading frame were measured in different growth phases. LÄS MER

4. 18. Role of Melatonin, Neuropeptide S and Short Chain Fatty Acids in Regulation of Duodenal Mucosal Barrier Function and Motility

   Författare :Wan Salman Wan Saudi; Markus Sjöblom; Olof Nylander; Mark Berner-Hansen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 51Cr-EDTA; rat; in vivo; duodenum; enteric nervous system; paralytic ileus; parecoxib; bicarbonate secretion; motility; ethanol; HCl; melatonin; neuropeptide S; short chain fatty acids; chemosensing; Physiology; Fysiologi;

   Sammanfattning : The duodenal epithelium is regularly exposed to HCl, digestive enzymes, bacteria and toxins, and sometimes also to ethanol and drugs. The imbalance of aggressive factors in the intestinal lumen and mucosal barrier function increases the risk of tissue injury and inflammation. LÄS MER

5. 19. Role of prostaglandin E2 as a neuro-immune mediator in the cholinergic anti-inflammatory pathway

   Författare :Priya Revathikumar; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Therapeutic implications of cholinergic anti-inflammatory pathway (CAP) activation have marked the beginning of a novel treatment strategy of passing electrical impulses along the left vagus nerve to alleviate acute and chronic inflammatory conditions. Extensive work in understanding CAP through vagus nerve stimulation (VNS) have identified key molecular and cellular mechanisms involved in the α7 nicotinic acetylcholine receptor (nAChR) mediated control of inflammation. LÄS MER

7. 20. Immunochemical, biochemical and evolutionary studies on Micrurus nigrocinctus nigrocinctus venom toxins

   Författare :Alberto Alape-Girón; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Monoclonal antibody; Phospholipase A2; neurotoxin; myotoxin; protein evolution;

   Sammanfattning : Immunochemical, biochemical and evolutionary studies on Micrurus nigrocinctus nigrocinctus venom toxins Monoclonal antibodies (MAbs) were produced against venom proteins of M. nigrocinctus nigrocinctus, the medically most important elapid of Central America. LÄS MER