Sökning: "niche"

Visar resultat 16 - 20 av 287 avhandlingar innehållade ordet niche.

  1. 16. Mesenchymal niche contribution to normal and malignant hematopoiesis

    Författare :Lakshmi Sandhow; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Normal hematopoiesis is tightly regulated by hematopoietic microenvironment/niche in bone marrow (BM) via direct hematopoietic cell-niche cell interaction and factors secreted by various types of cellular niches. The BM niche consists of cells of mesenchymal cell origin including mesenchymal stem cells (MSCs) and progenitor cells (MPCs). LÄS MER

  3. 17. Helicobacter spp. – host interaction in the mucus niche

    Författare :Médea Padra; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter; mucin; glycosylation; adhesion;

    Sammanfattning : Helicobacter pylori is the most common human gastric pathogen, colonizing half of the world's population. Helicobacter suis colonizes the stomach of 60-95% of pigs at slaughter age and it is the most prevalent non-Helicobacter pylori Helicobacter species found in the human stomach causing severe gastric disorders. LÄS MER

  4. 18. Stem cells in the adult heart - 3D culture, isolation of side population cells and search for a stem cell niche

    Författare :Kristina Vukusic; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heart; cardiac stem cells; Stem cell niche; Atrioventricular junction; Side population; 3D culture;

    Sammanfattning : Cardiac tissue shows a poor regenerative capacity. From 2003 reports, mostly based on animal models, have showed existence of stem cells also in the heart. Using 14C measurements, a slow but steady turnover of the cardiac cells was shown in humans, around 1%/year. As a source for this regeneration endogenous stem cells have been suggested. LÄS MER

  5. 19. Understanding the role of bone marrow niche in myeloid malignancies

    Författare :Monika Dolinska; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Normal hematopoiesis is generated and maintained by rare hematopoietic stem cells (HSCs) through their capacity to self-renew and differentiate. This process is rigorously controlled, both by HSC-intrinsic molecular programs and extrinsic signals emitted by the local bone marrow (BM) microenvironment, the so-called HSC niche. LÄS MER

  7. 20. Coping with environmental change : Lessons from isotope studies in a sentinel species

    Författare :Matias Ledesma; Agnes Karlson; Marleen De Troch; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; stable isotope; compound-specific nitrogen stable isotope analysis; trophic niche; harmful algae blooms; contaminants; stress; reproductive success; environmental change; Baltic Sea; marin ekologi; Marine Ecology;

    Sammanfattning : Adaptive evolution and phenotypic plasticity are two key mechanisms by which natural populations avoid extinction in the face of environmental change. Evolutionary young systems, such as the Baltic Sea with low species diversity and steep environmental gradients, are good models for studying how wild populations cope with environmental changes, such as climate-induced alterations in food supply and exposure to environmental contaminants. LÄS MER