Sökning: "newt"

Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet newt.

  1. 1. Heart Regeneration : Lessons from the Red Spotted Newt

    Författare :Nevin Witman; Jamie Morrison; Thomas Braun; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Heart; Regeneration; Newt; microRNAs; RNA editing; Molecular Biology; molekylärbiologi;

    Sammanfattning : Unlike mammals, adult salamanders possess an intrinsic ability to regenerate complex organs and tissue types, making them an exciting and useful model to study tissue regeneration. The aims of this thesis are two fold, (1) to develop and characterize a reproducible cardiac regeneration model system in the newt, and (2) to decipher the cellular and molecular underpinnings involved in regeneration. LÄS MER

  3. 2. Regenerating the brain : lessons from the red spotted newt

    Författare :Daniel Berg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Unlike mammals, adult salamanders can regenerate their brain after injury in a process fuelled by neurogenesis. The aim of this thesis is to identify the cells that give rise to new neurons after injury and examine the mechanisms controlling the initiation and termination of brain regeneration in the newt. LÄS MER

  4. 3. Characterisation of newt neural stem cells during development and regeneration

    Författare :Shahul Hameed Liyakath Ali; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The adult newt brain has a unique potential to regenerate neurons after injury. Ependymoglial cells that line the ventricular system of the newt brain are critical for neuronal regeneration, since they reenter the cell cycle upon injury and differentiate into neurons. Ependymoglial cells share key features with radial glial cells in mammals. LÄS MER

  5. 4. Choosing the best of both worlds : the double life of the great crested newt

    Författare :Daniel Gustafson; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The great crested newt (Triturus cristatus) is dependent on two environments for its survival: the aquatic habitat necessary for breeding and development, and the terrestrial habitat required for post-breeding and juvenile activities. For a population to be able to survive in a landscape, both habitat types must be present within migration distance from each other. LÄS MER

  7. 5. Implementing new genomic tools to study ventral midbrain development and injury response in the newt Pleurodeles waltl

    Författare :Zeyu Yao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mammals have a poor ability to regenerate organs or tissues. In particular, brain neurons do not regenerate after damage. A good example of this limitation is the irreversible degeneration of midbrain dopaminergic neurons in Parkinson’s disease (PD). Several strategies are being developed to treat PD. LÄS MER