Sökning: "neutrophils and tuberculosis"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden neutrophils and tuberculosis.

  1. 1. Mycobacterium tuberculosis and HIV coinfection : Effects on innate immunity and strategies to boost the immune response

    Författare :Anna-Maria Andersson; Robert Blomgran Julinder; Marie Larsson; Olle Stendahl; Susanna Brighenti; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Tuberculosis (TB) still remains a big threat today, being the leading cause of death by a single infectious agent. The TB epidemic is fueled by HIV along with the increasing drug-resistance which prolongs the already long treatment duration and decreases the success rate for curing TB. LÄS MER

  3. 2. Activation of neutrophils by mycobacteria and mycobacterial components

    Författare :Jenny Fäldt; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human neutrophils; mycobacteria; oxygen radicals; cytokines; mycobacterial glycolipids; priming;

    Sammanfattning : The genus Mycobacterium includes free-living saprophytes, opportunists, and human pathogens.Mycobacterium tuberculosis, the organism causing tuberculosis, as well as other pathogenicmycobacteria can survive and multiply inside phagocytic cells, but the underlying mechanisms areonly partly understood. LÄS MER

  4. 3. Innate immune responses to Mycobacterium tuberculosis infection : How extracellular traps and trained immunity can restrict bacterial growth

    Författare :Clara Braian; Maria Lerm; Olle Stendahl; Parasa Venkata Ramanarao; Nordenfelt Pontus; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis, and the cause of 1.5 million deaths in 2018. During a pulmonary TB infection, the bacterium reaches the lungs and is phagocytosed by cells of the innate immune system, primarily macrophages. LÄS MER

  5. 4. Apoptotic neutrophils enhance the immune response against Mycobacterium tuberculosis

    Författare :Alexander Persson; Olle Stendahl; Per-Arne Oldenborg; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar;

    Sammanfattning : Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, a disease that for years was considered to belong of the past, but tuberculosis is back causing over 2 million deaths per year. The infection can be dormant for decades and an active immune response can prevent the infection from progressing into active disease. LÄS MER

  7. 5. Mycobacterium tuberculosis and the human macrophage : shifting the balance through inflammasome activation

    Författare :Daniel Eklund; Maria Lerm; Olle Stendahl; Eva Särndahl; Norbert Reiling; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Mycobacterium tuberculosis is a very successful pathogen and tuberculosis constitutes a major threat to global health worldwide. The World Health Organization (WHO) estimates that almost nine million new cases and 1. LÄS MER