Sökning: "neutrophil granulocyte"

Visar resultat 6 - 10 av 33 avhandlingar innehållade orden neutrophil granulocyte.

  1. 6. C5a Receptor Expression in Severe Sepsis and Septic Shock

    Författare :Mia Furebring; Jan Sjölin; Per Folllin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; C5a receptor; granulocyte; severe sepsis; septic shock; chemotaxis; anti-C5a treatment; ex vivo incubation; C5a; interleukin-8; LPS; Infektionssjukdomar; Infectious diseases; Infektionssjukdomar;

    Sammanfattning : In patients with sepsis, the activation of the cascade systems, for example the complement system with the generation of C5a, is followed by a state of immunosuppression with impaired bactericidal capacity caused by suppression of the neutrophil granulocytes. To inhibit the C5a-induced systemic inflammatory and the following anti-inflammatory responses, different anti-C5a strategies have been successful in experimental models of sepsis. LÄS MER

  3. 7. Redox effects on neutrophils in wound healing conducted by wound dressings and hyperbaric oxygen

    Författare :Herman Sahlin; Göteborgs universitet; []
    Nyckelord :neutrophil granulocyte; wound healing; wound dressing; reactive oxygen species; NO; hyperbaric oxygen; bacterial killing;

    Sammanfattning : The increased influx of neutrophils into chronic wounds results in increased production of reactive oxygen species (ROS), nitric oxide (NO) and lipid peroxidation products (LPP), as well as a ROS-induced increase in protease levels. The NO and LPP impair the respiratory burst response of the neutrophils and reduce their capacity to kill bacteria and digest debris. LÄS MER

  4. 8. Immunomodulatory Properties of 2-Hydroxyethyl Methacrylate

    Författare :Jennie Andersson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 2-Hydroxyethyl Methacrylate; Granulocyte; Respiratory burst; Immunoglobulin; B cell; Interleukin; Mouse;

    Sammanfattning : Immunomodulatory Properties of 2-Hydroxyethyl Methacrylate Jennie Andersson Department of Oral Microbiology and Immunology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg Professionals working in dentistry have reported adverse effects, such as allergic contact dermatitis, following exposure to 2-hydroxyethyl methacrylate (HEMA). Furthermore unpolymerized HEMA monomers leaking from cured fillings can reach the dental pulp, where HEMA could come into contact with leukocytes. LÄS MER

  5. 9. Signaling capacity of ß2-integrins in relations to neutrophil motility

    Författare :Ragnhild Löfgren; Linköpings universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; INTERDISCIPLINARY RESEARCH AREAS; TVÄRVETENSKAPLIGA FORSKNINGSOMRÅDEN;

    Sammanfattning : The neutrophil granulocyte is one of the most mobile cell types in the human body and represents the first line of defense against invading pathogens. Adhesion and chemotactic receptors on the cell surface work together through modulations of the cytoskeleton and thereby cause the cell to move. LÄS MER

  7. 10. Granulocyte activation by danger signals and blocking of receptor responses

    Författare :Anna-Lena Stenfeldt; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; granulocytes; neutrophils; eosinophils; danger signals; danger theory; formyl peptide receptors; antagonists; inhibitors;

    Sammanfattning : Granulocytes are the most abundant cells in the peripherial blood. They serve to eliminate invading microbes and parasites and release anti-microbial agents. In the event of injury, granulocytes are recruited to damaged tissues. LÄS MER