Sökning: "neutrophil granulocyte"

Visar resultat 21 - 25 av 33 avhandlingar innehållade orden neutrophil granulocyte.

  1. 21. Phagocytic-receptor signaling in human neutrophils

    Författare :Ragnhild Löfgren; Matthias P. Wymann; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The neutrophil granulocyte is one of the most mobile cells in the body and through a number of functions represents the first line of defense against invading pathogens. Adhesion and chemotactic receptors on the cell surface work together through modulation of the cytoskeleton, thereby enabling cell movement. LÄS MER

  3. 22. Eosinophil Cationic Protein : Expression Levels and Polymorphisms

    Författare :Jonas Byström; Helene Rosenberg; Uppsala universitet; []
    Nyckelord :Medical sciences; Eosinophils; Neutrophils; Monocytes; Macrophages; mRNA; eosinophil cationic protein; DNA; polymorphism; Hodgkin Lymphoma; asthma; allergy; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Chemistry; klinisk kemi;

    Sammanfattning : The eosinophil cationic protein (ECP) is usually associated with the eosinophil granulocyte. In this thesis the presence and production of this protein has been studied in two other cells. The circulating monocyte was found to contain ECP mRNA and small amounts of ECP, one thousand times less than that found in the eosinophil. LÄS MER

  4. 23. Complement receptor-mediated signal transduction in human neutrophils : A role for protein kinase C in the phagocytic process

    Författare :Maria Fällman; Claes B. Wollheim; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The neutrophil granulocyte comprises the first line of human defense against invading microorganisms. A versatile motile machinery enables the cell to migrate to the inflammatory site and there engulf and destroy the pathogens by phagocytosis. LÄS MER

  5. 24. Pharmacometric Models for Improved Prediction of Myelosuppression and Treatment Response in Oncology

    Författare :Angelica L Quartino; Mats O Karlsson; Lena E Friberg; Etienne Chatelut; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacometrics; oncology; myelosuppression; chemotherapy; pharmacokinetics; pharmacodynamics; PHARMACY; FARMACI; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Sammanfattning : Chemotherapy plays an important role in the treatment of cancer. However, these drugs also cause death of non-malignant cells, resulting in severe side-effects. In addition, drug resistance may exist. Predictive tools for dose and drug selection are therefore warranted. LÄS MER

  7. 25. Separation and Further Characterization of Hematopoietic Cell Populations Based on Phenotypic and Biophysical Properties

    Författare :Josefina Dykes; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoiesis; Blood Group; ABO-system; Hematopoietic Stem Cell Transplantation; Cell Separation;

    Sammanfattning : Hematopoietic stem cells (HSC) are multipotent and possess self-renewal capacity. Thus, they can sustain a life-long hematopoiesis and are also capable of restoring the hematopoietic system when transplanted to a patient. LÄS MER