Sökning: "neutrophil elastase"

Visar resultat 16 - 20 av 31 avhandlingar innehållade orden neutrophil elastase.

  1. 16. Immune response and tumour cell detection in lymph nodes of head and neck cancer

    Författare :Åsa Kågedal; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Many patients with head and neck squamous cell carcinoma present with regional spread to the cervical lymph nodes. Lymph nodes metastases are today the most important factor influencing both the treatment and outcome for this type of cancer. LÄS MER

  3. 17. Serglycin-dependent mast cell-specific proteases and their potential interactions with Giardia intestinalis

    Författare :Zhiqiang Li; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Mast cells are located in mucosal and connective tissues throughout the body where they play important roles in immune reactions towards infections. Mast cell deficiency results in failure of clearance of the non-invasive intestinal protozoan parasite Giardia intestinalis in mice, but the mast cell-driven mechanisms remain poorly understood. LÄS MER

  4. 18. Chronic Obstructive Pulmonary Disease: Role of Alpha-1-antitrypsin

    Författare :Ruta Aldonyte; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Andningsorganen; Respiratory system; monocytes; inflammation; AAT polymerization; AAT; COPD;

    Sammanfattning : The only proven genetic risk factor for Chronic Obstructive Pulmonary Disease (COPD) is an inherited Z (Glu342¡úLys) deficiency of alpha-1-antitrypsin (AAT), a major inhibitor of neutrophil elastase. In vivo, AAT is found in both native (inhibitory) and modified (non-inhibitory) forms. LÄS MER

  5. 19. On Mechanisms Impairing Airway Host Defence in Cystic Fibrosis

    Författare :Sandra Jovic; allergologi och palliativ medicin Lungmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Cystic fibrosis is an inherited disease, caused by mutations of the cystic fibrosis transmembrane conductance regulator gene. The gene codes for a protein that serve as chloride channel. In cystic fibrosis, this protein is lacking or has a defect function resulting in a thick and sticky mucus of the airways. LÄS MER

  7. 20. Severe and moderate alpha-1-antitrypsin deficiency at the age of 30

    Författare :Elisabeth Bernspång; allergologi och palliativ medicin Lungmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cohort; screening; alpha-1-antitrypsin; lung function; CT densitometry; liver;

    Sammanfattning : Alpha-1-antitrypsin (AAT) is a glycoprotein synthesised in the liver. Its main role is to protect lung tissue from destruction by neutrophil elastase. In severe (PiZZ) AAT deficiency, there is an increased risk of emphysema, especially in smokers. LÄS MER