Sökning: "neutrophil elastase"

Visar resultat 11 - 15 av 31 avhandlingar innehållade orden neutrophil elastase.

  1. 11. Interleukin-17 in non-allergic airway inflammation

    Författare :Martti Laan; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IL-17; airway inflammation; bronchial epithelial cells; neutrophils; T-lymphocytes; IL-8; IL-6; MAP kinases.;

    Sammanfattning : Chronic bronchitis, chronic obstructive pulmonary disease (COPD), bronchial asthma and cystic fibrosis are common clinical disorders all characterized by airway neutrophilia. By releasing proteolytic enzymes and free oxygen radicals, neutrophils can contribute to the main features of these diseases such as airway obstruction, hypersecretion and remodelling. LÄS MER

  3. 12. Serine protease inhibitors in the upper and lower airways

    Författare :Camilla Hollander; Enheten för kroniska inflammatoriska och degenerativa sjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; auditive system and speech; Neutrophils; audiology; Otorhinolaryngology; Medicin människa och djur ; AAT; Medicine human and vertebrates ; SLPI; cytokines chemokines; anti-proteases; audiologi; hörsel- och talorganen; Airway inflammation; Otorinolaryngologi;

    Sammanfattning : Proteases and their inhibitors are implicated in the physiology and pathology of the airways. Protease inhibitors include those produced locally, such as secretory leukocyte protease inhibitor (SLPI), and those produced mainly by the liver that can reach the airways via passive diffusion, such as alpha1-antitrypsin (AAT). LÄS MER

  4. 13. The role of red blood cells in inflammation and remodeling

    Författare :Karin Fredriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Red blood cells; fibroblast; inflammation; remodeling; fibrosis;

    Sammanfattning : Besides being carriers of oxygen and carbon dioxide, red blood cells (RBCs) also have a scavenger function, binding inflammatory mediators to surface receptors. Animal and experimental models have suggested a role for RBCs in inflammatory and fibrotic responses and patients with idiopathic pulmonary hemosiderosis, a disease characterized by lung hemorrhage, frequently develop fibrosis. LÄS MER

  5. 14. Translational PET imaging of inflammation

    Författare :Emmi Puuvuori; Olof Eriksson; Tove Grönroos; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PET imaging; Nuclear Medicine; Inflammation; Translational Medicine;

    Sammanfattning : Inflammation is our body’s sophisticated defense mechanism against invading pathogens, traumas, and tumors. Repeatable and non-invasive monitoring of inflammation process would open opportunities to improve our knowledge of several diseases and enable assessment of personalized treatments. LÄS MER

  7. 15. Alpha 1-antitrypsin: A Role in Cancer Progression

    Författare :Inga Zelvyté; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; onkologi; Cytologi; cancerology; oncology; Cytology; invasion; neutrophils; cancer cell; Alpha1- antitrypsin; proteinase inhibitors;

    Sammanfattning : Alpha1-antitrypsin (AAT), a circulating single-chain glycoprotein is the most abundant serine proteinase inhibitor in human plasma. AAT is an acute phase protein, its levels increase rapidly to concentrations exceeding 50mM in response to inflammation, infection and malignant diseases. LÄS MER