Sökning: "neurotrophins"
Visar resultat 11 - 15 av 56 avhandlingar innehållade ordet neurotrophins.
11. Peripherally administered choleocystokinin-8 increases neurotrophins in the brain
Sammanfattning : The aim of this thesis was to test the hypothesis that the gastric hormone Cholecystokinin-8 (CCK-8) can modulate the production of Nerve Growth Factor (NGF) in the brain. NGF is the first discovered and the best characterized neurotrophic factor which plays a crucial role in the survival and development of basal forebrain cholinergic neurons (BFCN). LÄS MER
12. Effects of neonatal handling and enriched environment on neurotrophins and cognitive function
Sammanfattning : Environmental stimulation plays a critical role in the development and maintenance of behaviours and neural processes. Two experimental models that have guided research on behavioural and neural plasticity are Postnatal handling and Environmental enrichment. LÄS MER
13. Experimental Stroke and Neurotrophins: Regulation, function and gene transfer of neurotrophins in rat and mouse models of focal cerebral ischemia
Sammanfattning : Stroke caused by focal cerebral ischemia is a major cause of death and neurological disability in humans. The forebrain region most commonly affected by ischemic incidents is that supplied by the middle cerebral artery. LÄS MER
14. Biochemical and biophysical aspects of molecular recognition and signalling by neurotrophins
Sammanfattning : Neurotrophins are members of a family of structurally and functionally related neurotrophic factors that control the development and maintenance of the nervous system. There are currently 5 members which make up this family: nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), neurotrophin-4(NT-4) and neurotrophin-6 (NT-6), which so far is only described in fish. LÄS MER
15. Regulation of neurotrophins and their receptors : molecular aspects and functional implications
Sammanfattning : The aim of this work was to study the regulation of neurotrophins and their receptors in a functional aspect. The studies included analysis of neuronal and glial neurotrophin gene expression, that was investigated by using molecular biological techniques. LÄS MER