Sökning: "neuropeptide Y receptor"

Visar resultat 11 - 15 av 59 avhandlingar innehållade orden neuropeptide Y receptor.

  1. 11. Molecular evolution of the neuropeptide Y receptor family : Insights from mammals and fish

    Författare :Amanda Wraith; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Neurovetenskap; Neurology; Neurologi; Neurology; neurologi;

    Sammanfattning : Most genes in the genomes of vertebrates form families with multiple members that are more or less closely related. This thesis concerns investigations of the neuropeptide Y (NPY) family of peptides and the family of receptors to which these peptides bind, the NPY receptors. LÄS MER

  3. 12. Evolution of the Neuropeptide Y and Opioid Systems and their Genomic Regions

    Författare :Görel Sundström; Dan Larhammar; Manfred Schartl; Uppsala universitet; []
    Nyckelord :neuropeptide Y; opioid; evolution; genome duplication; gene duplication; Hox; SCN; IGFBP; MEDICINE; MEDICIN;

    Sammanfattning : Two whole genome duplications (2R) occurred early in vertebrate evolution. By using combined information from phylogenetic analyses and chromosomal location of genes, this thesis delineates the evolutionary history of two receptor-ligand systems that expanded by these large scale events. LÄS MER

  4. 13. A study of the structural requirements for receptor recognition of the neuropeptides substance P, neuropeptide Y and galanin

    Författare :Claudio Rivera; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  5. 14. Advancing gene therapy for epilepsy. Translational pre-clinical studies with neuropeptide Y and glial cell-line derived neurotrophic factor

    Författare :Esbjörn Melin; Epilepsicentrum; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epilepsy; Gene Therapy; neuropeptide Y NPY ; Y2 receptor; GDNF; Encapsulated cell biodelivery; seizure; In-vivo;

    Sammanfattning : Epilepsy is a neurological disorder, affecting approximately 1% of the population. The high rate of drug-resistance in epilepsy in general (30%), and temporal lobe epilepsy (TLE) in particular, pose a serious clinical problem. Thus, novel treatments for drug-resistant epilepsy is highly warranted. LÄS MER

  7. 15. Pharmacological Studies of Four Neuropeptide Y-family Receptor Subtypes

    Författare :Paula Sjödin; Dan Larhammar; Nina Mohell; Nigel Levens; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; Farmakologi; Pharmacological research; Farmakologisk forskning;

    Sammanfattning : The neuropeptide Y (NPY) family of structurally related peptides includes NPY, peptide YY (PYY) and pancreatic polypeptide (PP). They bind to G-protein coupled receptors named Y receptors, and include in mammals Y1, Y2, Y4, Y5, Y6 and in non-mammalian vertebrates also Y7, Yb and Yc. LÄS MER