Sökning: "neuropeptide 1: noradrenaline"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden neuropeptide 1: noradrenaline.

  1. 1. Neuropeptide Y - aspects of vasomotorresponses and receptor characterization

    Författare :Torun Nilsson-Bergdahl; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vasoconstriction; RT-PCR; receptor characterization; potentiation; NPY Y1 receptor; NPY; mitogenesis; hypertension; human arteries; forearm blood flow; cell culture; antisense oligodeoxynucleotides; BIBP3226; vasodilatation.; Physiology; Fysiologi; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : Abstract The aims of the present thesis were to examine neuropeptide Y (NPY) responses in different human and guinea pig vascular beds and in cultured human vascular smooth muscle cells (VSMC) and to characterize, with different NPY agonists and the specific NPY Y1 receptor antagonist (BIBP3226), the NPY receptors involved. NPY-induced strong and potent contractions in human cerebral and subcutaneous arteries and in guinea pig basilar arteries. LÄS MER

  3. 2. Cholecystokinin, dopamine and glutamate in subcortical and peripheral control of food intake

    Författare :Min Qian; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :cholecystokinin; dopamine; glutamate; food intake;

    Sammanfattning : This thesis analyzes some of the mechanisms whereby cholecystokinin octapeptide (CCK-8) inhibits food intake in male rats. Depletion of monoamines using reserpine blocked the capacity for ingestive responses. These responses were restored in reserpinized rats by treatment with the non-competitive N-methyl-D-aspartate receptor antagonist MK-801. LÄS MER

  4. 3. Experimental, mild blast-induced traumatic brain injury : focus on the monoamine and galanin systems

    Författare :Lizan Kawa; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Traumatic brain injury (TBI) is a common cause of mortality and morbidity among civilians and servicemen alike. The spectrum of TBIs encompasses mild to severe cases, with the predominate number of TBIs being mild (mTBI). Combat-related TBI inflicted by explosive blast (bTBI) is highly prevalent among military personnel. LÄS MER

  5. 4. Ventricular fibrillation and defibrillation in patients with implantable cardioverter defibrillators

    Författare :Mikael Runsiö; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :ventricular fibrillation; defibrilla~ion; implantable cardioverter defibrillator; haemodynamic; metabolism; hyperaemia; ischaemia; myocardial injury; histamine; neuropeptide 1: noradrenaline; endothelin; histamine; positron emission tomography.;

    Sammanfattning : Since the introduction of the implantable cardioverter defibrillator for humans with malignant ventricular arrhythmias in 1980, over 50, 000 patients world wide have received this device. The implantation procedure is simple and resembles the implantation of an ordinary pacemaker. LÄS MER

  7. 5. Effects of fractionated irradiation on salivary glands

    Författare :Lars Franzén; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Salivary glands; irradiation; xerostomia; acinar cells; secretion; cell membrane; neuropeptides;

    Sammanfattning : The thesis is a study of the effects of radiation on the salivary glands in an experimental and a clinical study. Irradiation is a cornerstone in the management of head and neck cancer and is as other modalities of cancer treatment, afflicted with adverse reactions. LÄS MER