Sökning: "neurology"

Visar resultat 6 - 10 av 457 avhandlingar innehållade ordet neurology.

  1. 6. Experimental Stroke and Neurotrophins: Regulation, function and gene transfer of neurotrophins in rat and mouse models of focal cerebral ischemia

    Författare :Gunnar Andsberg; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsychology; Neurology; animal behaviour; striatum; stereology; immunohistochemistry; focal cerebral ischemia; nerve growth factors; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : Stroke caused by focal cerebral ischemia is a major cause of death and neurological disability in humans. The forebrain region most commonly affected by ischemic incidents is that supplied by the middle cerebral artery. LÄS MER

  3. 7. Neuroprotection and neurogenesis after experimental stroke

    Författare :Andreas Arvidsson; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; stereology; rat; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; BrdU; immunohistochemistry; in situ hybridization; subventricular zone; striatum; dentate gyrus; neuronal replacement; neuronal survival; Focal cerebral ischemia; glial cell line-derived neurotrophic factor;

    Sammanfattning : In this thesis, two potential endogenous mechanisms for neuronal survival and repair have been investigated in a rat model of stroke, middle cerebral artery occlusion (MCAO): signaling of the GDNF family of neurotrophic factors, and neurogenesis from endogenous progenitor cells. As determined by in situ hybridization for GDNF family ligand and receptor genes, MCAO caused widespread upregulation of both components of the functional GDNF receptor, c-Ret and GFRalpha1, indicating that GDNF may be a survival signal in stroke. LÄS MER

  4. 8. Functional brain imaging of sensorimotor dysfunction and restoration : investigations of discomplete spinal cord injury and deep brain stimulation for essential tremor

    Författare :Amar Awad; Johan Eriksson; Patric Blomstedt; Richard Levi; Lars Nyberg; Rick Helmich; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sensorimotor control; fMRI; discomplete spinal cord injury; essential tremor; deep brain stimulation; cerebello-thalamo-cerebral circuit; Physiology; fysiologi; neurokirurgi; Neurosurgery; Neurology; neurologi; rehabiliteringsmedicin; Rehabilitation Medicine;

    Sammanfattning : The nervous system exists to generate adaptive behaviour by processing sensory input from the body and the environment in order to produce appropriate motor output, and vice versa. Consequently, sensorimotor dysfunction is the basis of disability in most neurological pathologies. LÄS MER

  5. 9. Muscle Thixotropy : Implications for Human Motor Control

    Författare :Hans Axelson; Karl-Erik Hagbarth; Mikael Elam; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Motor control; Skeletal muscle; Thixotropy; History-dependent; EMG; Voluntary contractions; Neurovetenskap; Neurology; Neurologi;

    Sammanfattning : Human skeletal muscles possess thixotropic, i.e. history-dependent mechanical properties. This means that the degree of passive muscle stiffness and resting tension is dependent on the immediately preceding history of contractions and length changes. LÄS MER

  7. 10. Effects of ionising and non-ionising radiation in cell systems and a rat model for immuno-therapy

    Författare :Catrin Baureus Koch; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kirurgi; ortopedi; traumatologi; Neurology; traumatology; transplantation; Surgery; orthopaedics; cell cultures; abscopal effect; serologi; Immunologi; serology; Immunology; rat tumour model; radiation therapy; radiation sterilisation; pulsed electric fields; interferon-gamma; immuno-gene therapy; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; glioblastoma multiforme;

    Sammanfattning : The most malignant brain tumour, glioblastoma multiforme (GBM), has an utterly bad prognosis. In spite of all available therapy, the mean survival time is less than a year. In the unique BRIGTT project (Brain Immuno Gene Tumour Therapy), patients at the Dept of Neurosurgery. LÄS MER