Sökning: "neurological models"

Visar resultat 1 - 5 av 85 avhandlingar innehållade orden neurological models.

  1. 1. Proteomics in neurological disease

    Författare :Jan Ottervald; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Neurodegenerative and neuroinflammatory diseases are conditions affecting the central nervous system that in the end have dramatic impacts on the affected individuals and their families. Today, large efforts are made to understand the disease origin and progression. LÄS MER

  3. 2. Diffusion MRI with generalised gradient waveforms : methods, models, and neuroimaging applications

    Författare :Deneb Boito; Evren Özarslan; Magnus Herberthson; Anders Eklund; Ida Blystad; Frederik Laun; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Diffusion; Diffusion MRI; Microstructure; Brain; White matter; Microscopic anisotropy; Constrained optimisation;

    Sammanfattning : The incessant, random motion of water molecules within biological tissues reveals unique information about the tissues’ structural and functional characteristics. Diffusion magnetic resonance imaging is sensitive to this random motion, and since the mid-1990s it has been extensively employed for studying the human brain. LÄS MER

  4. 3. Losing control and developing concerns : The complexities of ageing postural control and fall-related concerns

    Författare :Mascha Pauelsen; Lars Nyberg; Ulrik Röijezon; Irene Vikman; Jorunn Lægdheim Helbostad; Luleå tekniska universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ageing; postural balance; postural control; sensory and motor systems; fall-related concerns; fear of falling; neurological models; Physiotherapy; Fysioterapi;

    Sammanfattning : With the world population shifting its proportions towards higher ages, it is imperative to increase healthspan rather than lifespan, both for the sakes of community sustainability as well as individual quality of life. One of the main means to obtain healthy ageing, is a concept called active ageing, as activity has shown to slow down the natural ageing process. LÄS MER

  5. 4. Functional MRI characterization of animal models of parkinsonism

    Författare :Cyril Monnot; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Parkinson's disease (PD) is the second most common neurological disorder. It is characterized by the progressive development of motor symptoms - bradykinesia, resting tremor, muscular rigidity and difficulty with postural control - which serve as criterias for its clinical diagnosis. LÄS MER

  7. 5. Cellular models of human brain disorders from skin to brain

    Författare :Mansoureh Shahsavani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Studying human brain development and disorders is very challenging. In the absence of comparable model organisms, human-related models, and limitations to obtain live cells from the human brain, induced Pluripotent Stem Cell (iPSC) technology, in particular, provided a unique tool to study the disease mechanisms and investigate potential treatments. LÄS MER