Sökning: "neuroendocrine tumour"

Visar resultat 21 - 25 av 28 avhandlingar innehållade orden neuroendocrine tumour.

1. 21. Hypoxia and differentiation in human neuroblastoma cells

   Författare :Helén Nilsson; Institutionen för translationell medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ontogeny; embryology human ; Utvecklingsbiologi; teratologi; embryologi människa ; teratology; cytogenetik; Development biology; cytogenetics; Genetik; Genetics; Medicin människa och djur ; HIF; Medicine human and vertebrates ; MYCN; Hypoxia; differentiation; Neuroblastoma;

   Sammanfattning : The childhood tumour neuroblastoma is derived from immature cells of the sympathetic nervous system, which have become arrested at different maturation stages. Neuroblastoma is a malignancy with a high degree of heterogeneity, and there is a correlation between a poor differentiation status and a more aggressive phenotype. LÄS MER

3. 22. Clinical and immunohistochemical studies of small bowel carcinoid tumours

   Författare :Kalle Landerholm; Johannes Järhult; Nils Wierup; Sture Falkmer; Roland Andersson; Bo Wängberg; Linköpings universitet; []
   Nyckelord :;

   Sammanfattning : Small bowel carcinoid tumours arising from enterochromaffin cells in the jejunum and ileum are neuroendocrine tumours (NETs) characterized by secretion of serotonin, tachykinins and other bioactive substances. These substances may lead to the typical carcinoid syndrome as well as pronounced fibrosis locally and in the heart. LÄS MER

4. 23. Hormonal programming and adrenal function. Studies in children and in a rat model

   Författare :Jovanna Dahlgren; Göteborgs universitet; []
   Nyckelord :Children; cortisol; dehydroepiandrosterone sulphate; small for gestational age; short stature; cytokines; dexamethasone; insulin sensitivity; androgenization;

   Sammanfattning : Prenatal events during specific time windows have been found to be followed by permanent changes affecting neuroendocrine, so called programming. Undernutrition, placental dysfunction or maternal stress, are apparent examples of such stimuli. LÄS MER

5. 24. Stress susceptibility, beta-blocker use and cancer survival

   Författare :Ruzan Udumyan; Katja Fall; Scott Montgomery; Fang Fang; Edoardo Botteri; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Stress resilience; β-blockers; primary cancer; survival analysis; overall mortality; cancer-specific mortality; register-based cohort study;

   Sammanfattning : Accumulating evidence suggests that chronic stress may influence tumour biology through activation of neuroendocrine pathways and thus impair survival. However, measuring stressful exposures and their influence on health is challenging, partly due to substantial inter-individual variation in stress susceptibility. LÄS MER

7. 25. Statistical assessment of genomic variability in tumours and bacterial communities

   Författare :Anna Rehammar; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; somatic mutations; hierarchical Bayesian modelling; cancer genetics; high-throughput sequencing; metagenomics; personalised diagnostics;

   Sammanfattning : Current high-throughput DNA sequencing technologies have the ability to generate large amounts of high-resolution genomic data. The high dimensionality in combination with the substantial levels of technical errors and biological variability typically present in the data make, however, the analysis challenging. LÄS MER