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Visar resultat 16 - 20 av 28 avhandlingar som matchar ovanstående sökkriterier.

  1. 16. Strategies for optimisation of 177Lu-octreotate therapy – exploring local administration and combination therapy regimens

    Författare :Viktor Sandblom; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peptide receptor radionuclide therapy; PRRT; 177Lu-octreotate; Neuroendocrine tumours; Optimisation; Local administration; Combination therapy;

    Sammanfattning : Neuroendocrine tumours (NETs) are a group of heterogeneous tumour types that originate in hormone-producing organs. Patients with NETs are often diagnosed after the primary tumour has metastasised. LÄS MER

  3. 17. Molecular characterization of FOX factors and Wnt signalling interplay in human cancers

    Författare :Giulia Pizzolato; Stefan Koch; Åsa Keita; Boudewijn Burgering; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; FOX proteins; Wnt signalling; p53; Tumour biology; Transcription factors; Proteine FOX; Via di segnalazione Wnt; p53; Biologia dei tumori; Fattori di trascrizione;

    Sammanfattning : Wnt/β-catenin signalling, also referred to as canonical Wnt signalling, is a critical regulator of tissue homeostasis and of the differentiation of cells during development. The outcome of canonical Wnt pathway activity is defined by the regulation of target gene transcription, which ultimately determines cell identity and proliferation. LÄS MER

  4. 18. Melatonin and its receptors in the normal human gastrointestinal tract, pancreas and in small intestinal neuroendocrine tumours

    Författare :Fanny Söderquist; Janet Cunningham; Lisa Ekselius; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Melatonin, “the hormone of darkness” is well known to regulate sleep and circadian rhythm. However, melatonin is also present in numerous peripheral tissues and the number of actions assigned to this neurohormone is growing steadily. LÄS MER

  5. 19. Melatonin in the gastrointestinal tract

    Författare :Fanny Söderquist; Janet Cunningham; Annica Jacobson; Bodil Ohlsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; melatonin; MT1; MT2; gastointestinal tract; small intestinal neuroendocrine tumours; IBS; depression; anxiety; personality and affective disorder; Medicinsk vetenskap; Medical Science; Psychiatry; Psykiatri;

    Sammanfattning : Melatonin is recognised as the pineal hormone regulating sleep and circadian rhythm. It has also been identified in peripheral tissues (mainly in animals) and thought to display a variety of actions, including anti-inflammatory properties, regulation of gastrointestinal (GI) functions, glucose homeostasis and beneficial effects in different tumour types. LÄS MER

  7. 20. PET/CT with 18F-FDG and 68Ga-DOTATOC in pulmonary carcinoid imaging

    Författare :Natalja Uhlén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: PET/CT, positron emission tomography combined with computed tomography, with 18F-FDG (2-deoxy-2-[18F]fluoro-D-glucose) is well established in oncological imaging. Pulmonary carcinoid tumours may have metabolic activity, making them available for PET/CT imaging with 18F-FDG. LÄS MER