Sökning: "neural stem progenitor cells"

Visar resultat 16 - 20 av 101 avhandlingar innehållade orden neural stem progenitor cells.

1. 16. Mechanisms of Transgene Silencing in Neural Cells -Implications for Ex Vivo Gene Therapy to the Brain

   Författare :Nina Rosenqvist; Neurobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurophysiology; Neurologi; Neurology; neuropsychology; ChIP; rat; transgene; insulator; differentiation; GFP; lentivirus; DNA methylation; histone deacetylation; chromatin; expression; silencing; stem cell; progenitor; gene therapy; neurofysiologi; neuropsykologi; CNS; transplantation;

   Sammanfattning : The use of genetically modifi ed neural stem and progenitor cells could possibly be a future strategy for repairing a brain suffering from neurodegeneration. However, so far it has proven diffi cult to maintain sufficient levels of a transferred gene in suitable cell types, after transplantation. LÄS MER

3. 17. Modeling Neural Stem Cell and Glioma Biology

   Författare :Tobias Bergström; Karin Forsberg-Nilsson; Staffan Johansson; Sven Påhlman; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neural stem cell; integrins; glioma; PDGF; mast cell; Molekylär cellbiologi; Molecular Cellbiology; Oncology; Onkologi;

   Sammanfattning : This thesis is focused on neural stem cell (NSC) and glioma biology. I discuss how NSCs interact with extracellular matrix (ECM) proteins in the stem cell niche, and investigate the consequences of deregulated Platelet-derived growth factor (PDGF) signaling for embryonic NSCs in transgenic mice. LÄS MER

4. 18. Studies on adult stem cells

   Författare :Konstantinos Meletis; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : While our bodies are aging, in quite a few tissues, new cells are born every day, till the day we die. As you are reading this sentence, there is perhaps a new neuron born in your brain (and some are dying). LÄS MER

5. 19. Brain Regeneration - in vitro and in vivo studies of exercise-related effects on brain plasticity

   Författare :Cecilia Bull; Göteborgs universitet; []
   Nyckelord :brain; neural progenitor cells; stem cells; hippocampus; corpus collosum; rat; mouse; regeneration; neurogenesis; oligodendrogenesis; irradiation; exercise;

   Sammanfattning : Neural stem and progenitor cells in the germinal regions of the adult brain, such as the hippocampus, are of great interest, because they provide the possibility for enhanced brain plasticity or can contribute to endogenous cell replacement after injury or disease. Voluntary exercise was recently shown to robustly induce cellular and structural plasticity, thereby contributing to overall brain health. LÄS MER

7. 20. Functionalization and characterization of surface supported lipid membranes and their application in cell culture

   Författare :Dorota Thid; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; cell - surface interaction; supported phospholipid bilayer; IKVAV; DHA; stem progenitor cells; neural cells; surface analytical techniques; QCM-D; surface functionalization; peptide; cell differentiation; cell attachment; membrane; fatty acid;

   Sammanfattning : Phospholipid bilayers supported on a solid surface constitute a versatile, biomimetic platform for a variety of applications, such as biosensing, drug delivery research, cell engineering and as cell membrane mimics in fundamental cell research. Phosphocholine supported lipid bilayers are resistant to cell attachment in a wide range of conditions, and can be functionalized with bioactive signaling molecules to promote specific interactions with cells. LÄS MER