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Visar resultat 1 - 5 av 101 avhandlingar som matchar ovanstående sökkriterier.
1. Neural Stem and Progenitor Cells : Cellular Responses to Known and Novel Factors
Sammanfattning : Neural stem cell self-renewal and differentiation are tightly regulated events during CNS development, leading to cell division into new neural stem cells or the formation of neurons and glial cells. This thesis focuses on the cellular responses induced by known and novel factors in neural stem and progenitor cells (NSPCs). LÄS MER
2. Derivation, propagation and differentiation of human stem and progenitor cells
Sammanfattning : Neuronal loss is a common feature of many neurological disorders, including stroke, Parkinson’s disease, Alzheimer’s disease and traumatic brain injury. Human embryonic stem cells (hESCs) and hESC-derived neural progenitors (NPs) may provide a number of new ways for studying and treating diseases and injuries in the brain. LÄS MER
3. Neural Stem and Progenitor Cells as a Tool for Tissue Regeneration
Sammanfattning : Neural stem and progenitor cells (NSPC) can differentiate to neurons and glial cells. NSPC are easily propagated in vitro and are therefore an attractive tool for tissue regeneration. Traumatic brain injury (TBI) is a common cause for death and disabilities. A fundamental problem following TBI is tissue loss. LÄS MER
4. NEURAL STEM/PROGENITOR CELLS IN THE POST-ISCHEMIC ENVIRONMENT: Proliferation, Differentiation and Neuroprotection
Sammanfattning : Stroke is one of the leading causes of chronic disability and death in the Western world. Today, no treatment can repair the cellular loss associated with an ischemic lesion. LÄS MER
5. Transposable Elements in Neural Progenitor Cells
Sammanfattning : More than 90% of DNA does not code for proteins and for a long time these sequences were referred to as “junk DNA” due to their unknown purpose. With the advent of new technologies it is now known, that the non-coding part of the genome is of great importance for regulating gene expression and is therefore indispensable. LÄS MER