Sökning: "neural specification"
Visar resultat 21 - 25 av 50 avhandlingar innehållade orden neural specification.
21. Specification of the lens and olfactory placodes and dorsoventral patterning of the telencephalon
Sammanfattning : The vertebrate nervous system is a highly complex and intriguing structure with diverse functions. To understand the functional nervous system, we first have to be aware of how it is assembled during development. LÄS MER
22. Directed differentiation of adult neural stem cells for cell therapy in the nervous system
Sammanfattning : The emergence of neural stem cell research has raised hopes for cell therapy of neurological disorders. Insight into the normal mechanisms of neural stem cell fate specification and differentiation is a prerequisite for the development of safe and efficient clinical applications. LÄS MER
23. Journeys in vector space: Using deep neural network representations to aid automotive software engineering
Sammanfattning : Context - The automotive industry is in the midst of a transformation where software is becoming the primary tool for delivering value to customers. While this has vastly improved their product offerings, vehicle manufacturers are facing an urgent need to continuously develop, test, and deliver functionality, while maintaining high levels of quality. LÄS MER
24. The role of transcriptional repression in Shh signalling and patterning of the ventral neural tube
Sammanfattning : From flies to humans, members of the Hedgehog (Hh) family of secreted signalling molecules play a vital role in determining cell fate and patterning during embryonic development. In vertebrates, Sonic Hedgehog (Shh) act in a graded manner to establish distinct neural progenitor populations at different concentration thresholds in the ventral neural tube. LÄS MER
25. DNA fragility in the context of neural stem cell fate : a multi-method integrative exploration of genome dynamics
Sammanfattning : Recent advances in mapping the complex genetic architecture underlying various debilitating brain disorders have enabled identification of several genetic risk variants. However, these risk variants only explain part of the heritability and vulnerability to these disorders in early development. LÄS MER