Sökning: "neural precursor"

Visar resultat 1 - 5 av 41 avhandlingar innehållade orden neural precursor.

  1. 1. Physiological role of amyloid precursor protein during neural development

    Författare :Rakesh Kumar Banote; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amyloid precursor protein; Zebrafish; Spinal cord; Motor neurons; Hindbrain; Mauthner cell; Development; Proteomics;

    Sammanfattning : Amyloid precursor protein (APP) is a type-one membrane-spanning protein with a large extracellular N-terminal domain and a small intracellular C-terminal domain. APP first gained interest due to its involvement in the pathogenesis of Alzheimer’s disease (AD). LÄS MER

  3. 2. Human neural precursor cells in spinal cord repair

    Författare :Junghua Piao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Traumatic spinal cord injury (SCI) often results in substantial neural cell death, axonal degeneration and demyelination, accompanied by loss of sensory and motor functions. Cell therapy may have neuroprotective effects, substitute for lost neural cells, promote regeneration and enhance remyelination in the lesioned spinal cord. LÄS MER

  4. 3. Assessment of precursor cell proliferation in normal and injured adult mammalian brains

    Författare :Hong Zhu; Göteborgs universitet; []
    Nyckelord :6-OHDA; astrocytes; cell proliferation; neural stem cells; ; neurogenesis; precursor cells; seizure; SVZ-OB pathway;

    Sammanfattning : In the adult mammalian brain, new neurons are generated from neural stem cells (NSCs) which reside in the subventricular zone (SVZ) of the lateral ventricle wall and in the subgranular zone (SGZ) of the dentate gyrus (DG) in the hippocampus. The biology of persistent NSCs in the adult brain is poorly understood. LÄS MER

  5. 4. Interactions between mouse CNS cells : microglia and neural precursor cells

    Författare :Johan Aarum; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Aggregate cultures; cell markers; CNS; differentiation; fetal; immunohistochemistry; microglia; migration; neural stem cells; phage display; precursor; Slit.;

    Sammanfattning : The mammalian central nervous system (CNS) contains a variety of cells, all specialized to perform different functions. Most numerous are the three types of glia cells, whose basic role is to support the signaling units of the CNS, the neurons. LÄS MER

  7. 5. Early Rostrocaudal Patterning of the CNS

    Författare :Ulrika Nordström; Thomas Edlund; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; CNS development; neural patterning; neural specification; Wnt; FGF; RA; Isthmic organizer; motor neurons; rostrocaudal patterning.; Developmental biology; Utvecklingsbiologi;

    Sammanfattning : The transformation of an initially uniform population of epiblast cells into an intricately complex central nervous system (CNS) is one of the most fascinating processes during embryonic development. Presumptive neural cells are initially specified as cells of forebrain character. LÄS MER