Sökning: "neural crest"

Visar resultat 1 - 5 av 68 avhandlingar innehållade orden neural crest.

  1. 1. Induction of the isthmic organizer and specification of the neural plate border

    Författare :Cédric Patthey; Lena Gunhaga; Thomas Edlund; Corinne Houart; Umeå universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; neural plate border; neural crest; placodes; Isthmic organizer; Wnt; BMP; FGF; Cell and molecular biology; Cell- och molekylärbiologi;

    Sammanfattning : The vertebrate nervous system is extremely complex and contains a wide diversity of cell types. The formation of a functional nervous system requires the differential specification of progenitor cells at the right time and place. LÄS MER

  2. 2. Neural crest in development and repair

    Författare :Jorge Benjamín Aquino; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis is focused on several aspects of neural crest biology, largely related to two main issues: 1) understanding its mechanisms of migration and 2) analyzing the potential of neural crest stem cells or their derivatives for nervous system repair. If repair is the aim, knowledge of both timing and events leading to axonal degeneration is required in order to block it and/or increase regeneration outcome. LÄS MER

  3. 3. The beneficial Effects of Neural Crest Stem Cells on Pancreatic      β–cells

    Författare :Anongnad Ngamjariyawat; Elena Kozlova; Leif Jansson; Jens Nielsen; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neural Crest Stem Cells; Pancreatic Islets; β-cell proliferation; β-cell survival; Cadherin; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Patients with type-1 diabetes lose their β-cells after autoimmune attack. Islet transplantation is a co-option for curing this disease, but survival of transplanted islets is poor. Thus, methods to enhance β-cell viability and function as well as methods to expand β-cell mass are required. LÄS MER

  4. 4. Cell-matrix interactions in neural crest development

    Författare :Roberto Perris; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  5. 5. Neural stam cells, TLX, and Neuroblastoma

    Författare :Ravi Kanth Rao Saini; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroblastoma; TLX; Neural Stem Cells; Dedifferentiation; DISC-1; DNA-PKcs;

    Sammanfattning : Neuroblastoma (NB) is one of the most commonly diagnosed extracranial tumors in children below five years of age. Moreover, NB accounts for almost 12-15% of all childhood cancer related fatalities. To date, the origin of NB has been linked to the neural crest derived sympathoadrenal progenitor cells. LÄS MER