Sökning: "netropsin"

Hittade 5 avhandlingar innehållade ordet netropsin.

  1. 1. DNA and RNA base analogue FRET - from fluorophore design to biochemical applications

    Författare :Moa Sandberg Wranne; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; adenine analogue; Fluorescent base analogue; FRET; thymine analogue; netropsin; fluorescence; DNA; RNA; Z-RNA;

    Sammanfattning : This thesis focuses on the development and use of fluorescent base analogues (FBAs). They are important tools in research concerning nucleic acids structure, dynamics and interactions. LÄS MER

  3. 2. Development of methods for optical mapping of nanoconfined DNA

    Författare :Lena Nyberg; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; competitive binding; optical mapping; YOYO-1; nanofluidics; antibiotic resistance; fluorescence microscopy; single-molecule; DNA; plasmids; netropsin;

    Sammanfattning : .... LÄS MER

  4. 3. Development of Methods for Single-Molecule Studies of DNA in Nanofluidic Channels

    Författare :Lena Nyberg; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; fluorescence microscopy; YOYO-1; Nanofluidics; netropsin; competitive binding; DNA; single-molecule;

    Sammanfattning : .... LÄS MER

  5. 4. Competitive-Binding Based Optical DNA Mapping - From Bacterial Plasmids to the Human Genome

    Författare :Vilhelm Müller; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; genetics; single-molecule; nanofluidics; DNA; antibiotic resistance; optical DNA mapping; plasmids; competitive binding; fluorescence microscopy; bacteria;

    Sammanfattning : Significant advances within the field of DNA sequencing have allowed us to study DNA at a level of detail that was previously impossible. However, dynamic genomic regions with a high degree of structural variations, while being linked to disease in humans and increased resistance to antibiotics, are still challenging to characterize. LÄS MER

  7. 5. Optical Mapping of Bacterial Plasmids

    Författare :Vilhelm Müller; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; competitive binding; optical mapping; fluorescence microscopy; DNA; plasmids; CRISPR Cas9; antibiotic resistance; nanofluidics; single-molecule;

    Sammanfattning : Bacteria that have acquired resistance to antibiotics represent one of the largest threats to human health and modern health care. The genes encoding resistance are frequently spread via the transfer of plasmids, which are circular double stranded DNA molecules separate from the chromosomal DNA of the bacteria. LÄS MER