Sökning: "netrin-1"

Hittade 4 avhandlingar innehållade ordet netrin-1.

  1. 1. Molecular and physiological functions of LRIG proteins and netrin-1 in health and disease

    Författare :Carl Herdenberg; Håkan Hedman; Richard Palmqvist; Maréne Landström; Aristidis Moustakas; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; LRIG; Netrin-1; LRIG1; LRIG2; LRIG3; Type 2 diabetes; Oncology; onkologi;

    Sammanfattning : The leucine-rich repeats and immunoglobulin-like domains (LRIG) gene family has three members, LRIG1, LRIG2, and LRIG3, that encode three structurally similar transmembrane proteins. LRIG1 is a receptor tyrosine kinase regulator, tumor suppressor, and stem cell marker in the skin, intestine, and brain. LÄS MER

  3. 2. Spinal Control of Locomotion : Developmental and Functional Aspects

    Författare :Nadine Rabe; Klas Kullander; Artur Kania; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuronal network; commissural interneuron; developmental interneuron subtypes; V3; mouse genetics; Pitx2; axon guidance; netrin-1; DCC; EphA4; Neuroscience; Neurovetenskap; Neuroscience; Neurovetenskap; Medicinsk utvecklings- och neurobiologi; Developmental Neurosciences; Molekylär genetik; Molecular Genetics;

    Sammanfattning : Neuronal networks are the central functional units of the nervous system. Knowledge about the identity of participating neurons and the assembly of these during development is crucial for the understanding of CNS function. LÄS MER

  4. 3. Crossing the Midline : Locomotor Neuronal Circuitry Formation

    Författare :Fatima Memic; Klas Kullander; Avihu Klar; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CPG; CIN; neuronal network; locomotion; left-right alternation;

    Sammanfattning : Networks at various levels of the nervous system coordinate different motor patterns such as respiration, eye or hand movements and locomotion. Intrinsic rhythm-generating networks that are located in the spinal cord generate motor behaviors that underlie locomotion in vertebrates. LÄS MER

  5. 4. Pain in rheumatoid arthritis : bone and neuroinflammation-associated mechanisms

    Författare :Resti Rudjito; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Pain is often the primary reason patients with rheumatoid arthritis (RA) seek medical care. Despite effective disease control with currently available disease modifying antirheumatic drugs (DMARDs), there are still hurdles to overcome as a significant proportion of patients still report continuous pain. LÄS MER