Sökning: "net present value"

Visar resultat 21 - 25 av 238 avhandlingar innehållade orden net present value.

  1. 21. Thymidylate synthase expression in colorectal cancer : its role as a prognostic factor and a predictive factor in adjuvant 5-fluorouracil-based chemotherapy

    Författare :David Edler; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Colorectal cancer; thymidylate synthase; immunohistochemistry; prognostic factor; 5-fluorouracil; adjuvant treatment;

    Sammanfattning : The enzyme thymidylate synthase (TS) plays a central role in DNA synthesis and is therefore an important target for chemotherapeutic treatment. We have studied the prognostic value of immunohistochemically detected TS on slices of formalin-fixed. paraffin embedded stored colorectal tumors using the monoclonal antibody TS 106. LÄS MER

  3. 22. Premature discharge from military service : risk factors and preventive interventions

    Författare :Helena Larsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Musculoskeletal injury; physiotherapy; intervention; conscript; soldier; functional tests; lower-limb-loading test; self-rated health; predictor;

    Sammanfattning : The tasks and capabilities of the Swedish Armed Forces are changing to meet new threats all around the world. With the sharp decrease in number of enlisted soldiers, selection is more important than ever. It is also important to prevent soldiers from leaving military service prematurely i.e. LÄS MER

  4. 23. Biomarkers in frontotemporal dementia : findings from the GENFI study

    Författare :Linn Öijerstedt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Frontotemporal dementia (FTD) is a group of neurodegenerative diseases including a wide range of clinical phenotypes, neuropathological hallmarks, and genetic causes. People with FTD typically present with deficits in behaviour and/or language which largely overlap with symptoms of other types of dementia and primary psychiatric disorders. LÄS MER

  5. 24. Positive and negative angiogenic factors in patients with malignant disease

    Författare :Christina Linder; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :angiogenesis; neovascularization; microvessel density; VEGF; bFGF; stromelysin-3;

    Sammanfattning : In this thesis, the levels of positive and negative angiogenic factors were studied in tissue, serum and urine from patients with malignant disease. The angiogenic factors VEGF (vascular endothelial growth factor) and bFGF (basic fibroblast growth factor) were studied in breast carcinomas. LÄS MER

  7. 25. Schizophrenia and criminal offending : risk factors and the role of treatment

    Författare :Åsa Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: The present thesis is written with the overall aim of advancing knowledge of criminal offending among individuals with schizophrenia. This may lead to better and more cost-effective methods for the prevention of criminal offending and, hopefully, to the reduction of public fear of mentally disordered persons. LÄS MER