Sökning: "nested case-control study"

Visar resultat 1 - 5 av 125 avhandlingar innehållade orden nested case-control study.

1. 1. Molecular epidemiology approach : nested case-control studies in glioma and lymphoid malignancies

   Författare :Florentin Späth; Beatrice S. Melin; Carl Wibom; Ann Sofie Johansson; Ingvar Bergdahl; Ola Landgren; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioma; B cell lymphoma; multiple myeloma; risk; repeated samples; prospective longitudinal study; nested case-control study; circulating sEGFR and sERBB2; circulating immune markers and growth factors; marker disease association; disease progression; NSHDS; Janus; linear mixed modeling; epidemiologi; Epidemiology; Oncology; onkologi;

   Sammanfattning : BACKGROUND: Nested case-control studies aim to link molecular markers with a certain outcome. Repeated prediagnostic samples may improve the evaluation of marker-disease associations. However, data regarding the benefit of repeated samples in such studies are sparse. LÄS MER

3. 2. Efficient design and analysis of extended case-control studies

   Författare :Bénédicte Delcoigne; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The nested case-control design is widely used in epidemiology for its efficiency, as it combines the advantages of both cohort and case-control designs. This design is an extension of the matched case-control design, where the matching variable is the time of occurrence of the outcome. LÄS MER

4. 3. Prospective studies of hormonal and life-style related factors and risk of cancer

   Författare :Sara Wirén; Pär Stattin; Håkan Jonsson; Tanja Stocks; Alicja Wolk; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; epidemiology; androgens; risk factors; fatherhood status; dizygotic twins; height; cohort; case-control; prospective; Cancer Epidemiology; cancerepidemiologi;

   Sammanfattning : Background: Androgens are important in prostate cancer development but how circulating levels of androgens affect risk of prostate cancer of different aggressiveness is not clear. Being childless has been associated with a lower risk of prostate cancer, but it is not clear if this association is causal or a result of residual confounding. LÄS MER

5. 4. Environmental risk factors for the occurrence of multiple sclerosis

   Författare :Martin Biström; Peter Sundström; Johan Hultdin; Jonatan Salzer; Kjell-Morten Myhr; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Multiple sclerosis; risk factors; epidemiology; case-control study; Human herpesvirus 6A; Human herpesvirus 6B; leptin; insulin; Epstein-Barr virus; vitamin D; Neurology; neurologi;

   Sammanfattning : Background. Multiple sclerosis (MS) is an inflammatory and degenerative disease of the central nervous system that typically debuts around age 30. About 2.3 million people are affected in the world today, and besides trauma it is the most common cause of neurological disability among young adults in the western world. LÄS MER

7. 5. Diet and postmenopausal breast cancer - With a focus on low-grade inflammation

   Författare :Joana Alves Dias; Nutritionsepidemiologi; []
   Nyckelord :Oxidative stress; low-grade inflammation; Biomarkers of inflammation; cytokines; ICC; variation; diet; dietary recommendations; diet quality index; food patterns; reduced rank regression; obesity; CVD; postmenopausal breast cancer; epidemiology; cross sectional; nested case-control;

   Sammanfattning : Diet-breast cancer studies have shown that “healthy eating patterns” are associated with decreased risk whereas unhealthy patterns (especially those including alcohol) are associated with increased risk, particularly in postmenopausal women. The potential mechanisms behind the observed associations are still under investigation. LÄS MER