Sökning: "nerve fibre"

Visar resultat 21 - 25 av 42 avhandlingar innehållade orden nerve fibre.

  1. 21. Studies in sporadic inclusion body myositis

    Författare :Snjólaug Arnardóttir; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord : s-IBM; muscle fibre regeneration; cytoskeleton; IVIg; muscle inflammtion; cytokine; training; sensibility; neuropathy ;

    Sammanfattning : Aims: The general aims of the present study were to increase the understanding of the disease process in s-lBM by analysing the cytoskeletal structure in muscle fibres and their regeneration potential; and also to evaluate sensory function in patients with s-IBM to test the hypothesis of an associated neurogenic component or a concomitant neuropathy in s-IBM; and to evaluate therapeutic options by analysing the effect of IVIg treatment on the muscle inflammation; and to evaluate the effect of training on muscle function and muscle inflammation. Patients: Twenty-six patients with the diagnosis of s41BM participated in these studies. LÄS MER

  2. 22. Machine Learning Algorithms for Improved Glaucoma Diagnosis

    Författare :Dimitrios Bizios; Oftalmologi (Malmö); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Primary open angle glaucoma, one of the leading causes of blindness in the world, constitutes a slow progressing condition characterized by damage to the optic nerve and retinal nerve fibre layer, and results in visual field defects afflicting the visual function. Highly specific and sensitive diagnostic tests able to detect the clinically significant glaucomatous changes in the structure of the nerve fiber layer and visual field are therefore required for the early detection and management of this disease. LÄS MER

  3. 23. Charcot-Marie-tooth disease : muscle morphological and neurophysiological aspects

    Författare :UllaBritt Ericson-Gripenstedt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Charcot-Marie-Tooth disease (CMT) is a common inherited disorder of the peripheral nervous system characterised by distal weakness and muscular atrophy, sensory disturbance of the distal limbs, diminished or absent deep tendon reflexes and often pes cavus. CMT is divided into two major groups based on clinical and electrophysiological findings. LÄS MER

  4. 24. Peptidergic innervation of periarticular tissue : a study in the rat

    Författare :Paul Ackermann; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Immunohistochemistry; radioimmunoassay; pain measurement; Achilles tendon; collateral ligaments; joint capsules; tendon rupture; regeneration; peripheral nervous system; neuropeptides; delta opioid receptor;

    Sammanfattning : Painful musculo-skeletal disorders pose a tremendous burden on the healthcare system, the main reason being the limited knowledge of the underlying pathomechanisms and lack of specific treatment. Hypothetically, the peripheral nervous system in the musculo-skeletal tissues plays an important role in the regulation of pain, inflammation, vasoactivity and also tissue repair. LÄS MER

  5. 25. On the interaction between a neuromuscular blocking agent and regulation of breathing during hypoxia

    Författare :Nicholas Wyon; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Neuromuscular block; TOF ratio; vecuronium; ventilatory response; chemoreceptors; carotid body;

    Sammanfattning : It was previously generally agreed that a mechanical train-of-four (TOF) ratio >0.70 represented an adequate recovery of respiratory function after neuromuscular blockade. Normal respiratory parameters at this level of recovery and during air breathing support this view. LÄS MER