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Visar resultat 1 - 5 av 10 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Point of care microfluidic tool development for resource limited settings

    Författare :Indradumna Banerjee; Aman Russom; Luca Brandt; Gustaf Mårtensson; Jens Ducrée; KTH; []
    Nyckelord :Blood; control; cell separation; centrifugal microfluidics; diagnostics; elasto-inertial; hematocrit level; microfluidics; neonatal diagnostics; nucleic acid quantification; point of care; particle focusing; resource limited settings.; Bioteknologi; Biotechnology;

    Sammanfattning : The development of point of care diagnostics using recent advances in microfluidics have the potential to transform health care in several ways, especially in resource limited settings with limited access to advanced health care infrastructure. However, translating a point of care device to reality is often a challenging task because of the complexities involved in integrating a number of diverse engineering concepts into an easy to use, accurate and portable device. LÄS MER

  3. 2. The dynamics of red blood cells and iron status during infancy

    Författare :Marie Larsson; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Barnreferensintervall; Röda blodkroppar; Erytrocyter; Extremt för tidig födsel; Erytropoes; Klinisk kemi; Järnstatus; Ferritin; sTfR; Neonatologi; Pediatrik; Fetal tillväxthämning; Referensintervall; Pediatric reference intervals; Reference limits; Extremely preterm birth; Fetal growth restriction; Clinical chemistry; Iron status; Red blood cells; Erythrocyte; Transfusion; Ferritin; sTfR; Hemoglobin; Neonatal; Reference intervals; Umbilical cord blood; Infancy; Iron deficiency; Anemia; Acute phase response; soluble Transferrin receptor; Neonatal intensive care; Erythropoiesis; Birth; Infant;

    Sammanfattning : Red blood cell (RBC) and iron status biomarkers are commonly used in clinical diagnostics. However, interpretations of infant test results are inherently challenging. LÄS MER

  4. 3. Congenital heart block : a study of diagnostics, pathogenesis, prognosis and treatment

    Författare :Håkan Eliasson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Congenital heart block (CHB) is a rare condition with considerable mortality. In most patients the disease is associated with fetal exposure to maternal SSA-Ro and/or SSB-La autoantibodies (AB) and develops in fetal life. Accuracy in fetal diagnostics is important to distinguish benign from life threatening conditions. LÄS MER

  5. 4. Children with congenital unilateral sensorineural hearing loss : etiology, newborn diagnostics, and hearing aid amplification

    Författare :Marlin Johansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Congenital unilateral sensorineural hearing loss (uSNHL) comprises about 25% of the sensorineural hearing losses (SNHLs) found through newborn hearing screening (NHS) programs. Even if children with congenital uSNHL struggle in school and everyday listening situations, studies on etiology, hearing aid (HA) outcomes and intervention are few, so it is still unknown when and how intervention is optimally provided. LÄS MER

  7. 5. Patent ductus arteriosus in extremely preterm infants : characteristics, risk factors and treatment decisions

    Författare :Anna Guðmundsdóttir; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Survival rates in infants born extremely preterm, before 28 weeks of gestation, are increasing and the focus has shifted towards decreasing morbidites after extremely preterm birth and promoting life-long health for the survivors.1-3Approximately 50-60% of extremely preterm infants have the past decade been treated for patent ductus arteriosus (PDA) to induce ductal closure. LÄS MER